Dallas, Texas Clinical Trials

A listing of Dallas, Texas clinical trials actively recruiting patient volunteers.

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Found 67 clinical trials
Multicenter Clinical Trial of a Phakic Implantable Collamer Lens (ICL)

This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian Implantable Collamer Lens (ICL) in study participants who have a diagnosis of myopia or myopia with astigmatism. Primary study analysis will be evaluated when 300 primary eyes complete 6 …

myopia
astigmatism
severe myopia
Key-Whitman Eye Center
 (9.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +13 other locations
Evaluation of GLR2007 for Advanced Solid Tumors

This study is designed to determine the safety, tolerability, and optimal dosing of GLR2007 in participants with advanced solid tumors that do not respond well to standard clinical therapies.

measurable disease
cancer therapy
contrast-enhanced magnetic resonance imaging
BRAF
recurrent disease
USA04
 (8.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
A Study of AK104 a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer

This is a Phase 2, global, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic cervical carcinoma.

major surgery
carcinoma
bevacizumab
pd-l1
cancer treatment
University of Texas Southwestern
 (3.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +19 other locations
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

atrophy
maculopathy
geographic atrophy
complement c5
age-related macular degeneration
Retina Foundation of the Southwest
 (7.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +22 other locations
First-in-Human Study of XMT-1592 in Patients With Ovarian Cancer and NSCLC Likely to Express NaPi2b

Phase 1b, a study in high grade serous ovarian cancer and nonsmall cell lung cancer to evaluate the safety and clinical activity of the antibody-drug conjugate (ADC) XMT-1592.

primary peritoneal carcinoma
non-small cell lung cancer
fallopian tube
peritoneal cancer
ovarian cancer
Mary Crowley Cancer Research Center
 (0.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +2 other locations
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

shortness of breath
regurgitation
fatigue
aortic valve replacement
Baylor Scott & White Research Institute
 (0.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery

The overarching goal of the study is to improve the surgical treatment outcomes of FAI, which is affecting an increasing number of military personnel and young active individuals in the general population. The proposed study will investigate critical patient, disease, and surgical treatment predictors of FAI surgery outcomes.

conservative management
arthroscopy
femoroacetabular impingement
hip arthroscopy
Texas Scottish Rite Hospital for Children
 (2.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +11 other locations
Pompe Disease Registry

The Pompe Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Pompe disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives …

glycogen storage disease type ii
replacement therapy
gaa gene
deficiency
myozyme
Investigational Site Number 840058
 (1.1 away) Contact site
  • 0 views
  • 22 Dec, 2020
  • +168 other locations
Fabry Disease Registry & Pregnancy Sub-registry

The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary …

alpha-galactosidase
fabry's disease
replacement therapy
deficiency
fabrazyme
Investigational Site Number 840058
 (1.1 away) Contact site
  • 0 views
  • 22 Dec, 2020
  • +125 other locations
Early Onset Alzheimer's Disease Genomic Study  

The purpose of this study is to collect samples from patients with Early-Onset Alzheimer's disease (AD) and their immediate family members for molecular analysis. Samples will be studied in order to understand how molecular changes in the body are related to the development of the disease. Researchers will study your …

severe dementia
alzheimer's disease
genetic testing
dementia
Baylor Scott & White AT&T Memory Center
 (7.5 away)
  • 0 views
  • 16 Feb, 2024
  • 1 location