Dallas, Texas Clinical Trials

A listing of Dallas, Texas clinical trials actively recruiting patient volunteers.

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Found 67 clinical trials
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

intermittent positive pressure ventilation
cough
malaise
sickle cell anemia
pharyngitis
B S & W Med Center
 (1.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia (ATLAS-NEO)

This is a multicenter, multinational, open-label, one-way cross-over, Phase 3, single-arm study for treatment of hemophilia. The purpose of this study is to measure the frequency of treated bleeding episodes with fitusiran in male adult and adolescent (≥12 years old) participants with hemophilia A or B, with or without inhibitory …

Children's Medical Center of Dallas Site Number : 8400018
 (4.8 away) Contact site
  • 0 views
  • 24 May, 2024
  • +53 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

tirzepatide
cardiovascular disease
body mass index
dulaglutide
Cardiovascular Research Institute of Dallas
 (7.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
positron emission tomography
florbetapir
alzheimer's disease
mini-mental state examination
Baylor AT&T Memory Center
 (7.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +85 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

migraine
treatment regimen
preventive medication
ly573144
lasmiditan
University of Texas Southwestern Medical Center at Dallas
 (3.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +162 other locations
A Study of Oral Tazemetostat in Subjects With Moderate and Severe Hepatic Impairment With Advanced Malignancies

This is a phase 1, 2-part, global, multicenter, open-label, PK, safety and tolerability study of oral tazemetostat in subjects with either advanced solid tumors, or hematological malignancies and normal hepatic function or moderate, or severe hepatic impairment.

prophylactic
sarcoma
targeted therapy
antimicrobials
systemic therapy
Mary Crowley Cancer Research
 (8.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy …

definitive treatment
chemoradiotherapy
neutrophil count
oral contraceptives
treatment regimen
UT Southwestern/Simmons Cancer Center-Dallas
 (3.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +254 other locations
A Randomized Trial Examining Plasma Exchange Using the Becton Dickinson (BD) Catheter In an Outpatient Apheresis Unit

This is a randomized pilot study of therapeutic apheresis procedures (TAP) using the current standard of care catheter (SOC) vs the BD Nexiva Diffusics Catheter. It is a single blinded, randomized study. Data will be used to refine and power a full randomized control trial. For this study, a sample …

Zale Lipshy Pavilion
 (3.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

anticonvulsants
melanoma
HRAS
recurrent hepatoblastoma
solid tumors
UT Southwestern/Simmons Cancer Center-Dallas
 (3.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

cataract
measurable disease
crizotinib
nf2 gene
neutrophil count
Childrens Medical Center - Univ. of Texas SW (Site 917)
 (4.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +16 other locations