Recruiting
VERITAC-2
A phase 3 study of ARV-471 compared to fulvestrant in adults with advanced ER+/HER2- breast cancer that has progressed after prior treatment
Learn moreCheck your eligibility now & get in touch with a study center
CHECK ELIGIBILITY
Together We Can Make Strides in Breast Cancer Research
Participating in these studies
Every study has unique requirements that determine who can participate.
Our clinical trial finder, powered by Leal Health, is an online questionnaire that can help see if you may be eligible to participate in a breast cancer study based on your health and medical history. It also gives you access to a dedicated member of the Leal Health Patient Support team who can answer your questions, help guide you in discussing your options with your oncologist and connect you to a study team (physician and nurses) to learn more. All the information you provide will be kept confidential.
The clinical trial finder can see if you may be eligible to participate in a breast cancer study sponsored by Pfizer and other organizations to maximize your opportunities to participate. To view our studies in more detail, please refer to the tiles below.
Our clinical trial finder, powered by Leal Health, is an online questionnaire that can help see if you may be eligible to participate in a breast cancer study based on your health and medical history. It also gives you access to a dedicated member of the Leal Health Patient Support team who can answer your questions, help guide you in discussing your options with your oncologist and connect you to a study team (physician and nurses) to learn more. All the information you provide will be kept confidential.
The clinical trial finder can see if you may be eligible to participate in a breast cancer study sponsored by Pfizer and other organizations to maximize your opportunities to participate. To view our studies in more detail, please refer to the tiles below.
Condition
Breast cancerAge
18+ yearsSex
Male and FemalePfizer Breast Cancer Clinical Trials
Recruiting
TACTIVE-U Studies
A phase 1b/2 study of ARV-471 when given with other medicines in people with ER+/HER-2 advanced or metastatic breast cancer
Learn moreRecruiting
C4391002
A phase 2 study of a combination therapy (PF-07220060 and PF-07104091) when given with endocrine therapy in adults with advanced or metastatic ER+/HER2- breast cancer
Learn moreNot yet recruiting
VERITAC-3
A phase 3 study of ARV-471 + palbociclib compared to letrozole + palbociclib in adults with previously untreated advanced ER+/HER2- breast cancer
Every clinical trial has unique requirements for participation. These requirements are called eligibility criteria and may include things like the stage of your cancer, the type of breast cancer you have, and any treatment you received in the past.
When considering if a specific clinical trial is a good fit for you, a doctor evaluates:
- The stage of the breast cancer (1 through 4) at diagnosis, which tells them how big the tumor is and if the cancer has spread outside of the breast(s)
- The tumor grade score (1 to 3). Grade 1 cells look more like normal cells compared to Grade 3 cells
- Whether this is first-time cancer or cancer that has returned after prior therapy
- Your age, menopausal status, overall health, and treatment preferences
Other things a doctor may consider in evaluating whether a specific clinical trial is right for you:
- Hormone receptor status: Some breast cancer cells have estrogen and/or progesterone receptors on their surface and require the hormones estrogen and/or progesterone to grow. This is described as being hormone receptor-positive, or HR-positive breast cancer.
- Human epidermal growth factor receptor 2 (HER2) status: HER2 is another kind of receptor found on the surface of some breast cancer cells. When there are too many HER2 receptors, it is described as HER2-positive breast cancer and can lead to uncontrolled breast cell division and tumor formation. Whether this is first-time cancer or cancer that has returned after prior therapy
- Triple-negative breast cancer (TNBC): Triple-negative breast cancer does not have any of the receptors commonly found in breast cancer, namely the receptors for estrogen, progesterone, or HER2.
Understanding common eligibility criteria in breast cancer clinical trials
Why participate in a clinical trial?
Before you decide to participate in one of our studies, we will review the study details with you including what you can expect to happen during the study, the length of participation, and potential risks and benefits.
Your safety and privacy are the highest priority while participating in any of our studies.
- Your participation in our clinical trials is voluntary, and you are free to withdraw at any time, for any reason.
- Your decision to stop being in a clinical trial will not affect your regular medical care or any benefits that you are entitled to.
If a Pfizer breast cancer study is a good fit for you and you decide to take part, you will receive:
- Close monitoring of your breast cancer during the study
- Access to investigational medicines or standard of care treatment (which is the established treatment currently used in people with your breast cancer type)
- The study medicine and any study-related procedures provided at no cost (these are generally covered by the sponsor)
- Reimbursement for any reasonable expenses that you may have as a result of taking part in the study such as parking, meals, or other travel-related expenses (check with your study team as this may vary)
- The opportunity to help advance scientific knowledge of breast cancer and potentially help other people with breast cancer in the future Why participate in a clinical trial?
While the majority of people with breast cancer are women, about 1% are male. And although non-Hispanic whites have higher rates of breast cancer, African American and blacks die at higher rates from breast cancer.
Many factors controlled by genetics, including race, ethnicity, and gender, can impact how people respond to a medicine and/or vaccine. That is why it is so important that clinical trials include people of all backgrounds.
Choosing to participate is very personal and many factors may weigh in your decision-making. Historically, there have been unjust practices in clinical research and barriers to access that have stood in the way of inclusive participation. Today, many protections are in place to better protect participants’ rights and safety and ensure that clinical trials are conducted ethically.
If you choose to participate, you must provide your consent (permission) before joining a study and can decide to withdraw from the study at any time, for any reason.
Your participation in a clinical trial may help advance potential investigational medicines for people across the globe. When everyone is accurately represented, we can improve the development of novel study medicines, learn how they work for different people, and reduce health disparities among underrepresented populations
Many factors controlled by genetics, including race, ethnicity, and gender, can impact how people respond to a medicine and/or vaccine. That is why it is so important that clinical trials include people of all backgrounds.
Choosing to participate is very personal and many factors may weigh in your decision-making. Historically, there have been unjust practices in clinical research and barriers to access that have stood in the way of inclusive participation. Today, many protections are in place to better protect participants’ rights and safety and ensure that clinical trials are conducted ethically.
If you choose to participate, you must provide your consent (permission) before joining a study and can decide to withdraw from the study at any time, for any reason.
Your participation in a clinical trial may help advance potential investigational medicines for people across the globe. When everyone is accurately represented, we can improve the development of novel study medicines, learn how they work for different people, and reduce health disparities among underrepresented populations
Representation is key
Learn more about the clinical trial experience
Hear from the Women of When We Tri(al)
People of color continue to be underrepresented in global clinical trials. Together, Pfizer, Inc. and the Tigerlily Foundation are helping to tackle barriers to equitable care for women of color and patient…
Watch video
Karen's Story
Karen, a stage 4 triple negative breast cancer survivor, shares her experience as a previous clinical trial participant.
Watch video
Deltra's Story
Deltra, as a metastatic breast cancer patient, talks about the importance of knowing your available treatment options.
Watch videoFrequently asked questions
What is breast cancer?
Breast cancer is a type of cancer that starts in one or both breasts; cancer begins when cells start to grow out of control. Though it occurs mostly in women, men can get breast cancer. Each year about 2.3 million people are diagnosed with breast cancer globally.
What is metastatic or advanced breast cancer?
Metastatic breast cancer—sometimes called advanced or Stage IV breast cancer—is breast cancer that has spread beyond the breast, most commonly to the lungs, bones, liver, and brain. It is the most advanced stage of breast cancer. Even though metastatic breast cancer is in another part of the body, it is still made up of breast cancer cells and is treated as breast cancer. There are a number of treatments and research options for people living with metastatic breast cancer.
Why are the Pfizer breast cancer clinical trials being conducted?
The Pfizer breast cancer clinical trials are being conducted to see if study medicines may help stop or slow the spread of breast cancer.
