Olaparib Clinical Trials

A listing of Olaparib medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 4 clinical trials
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

platinum-based chemotherapy
cancer
endometrial carcinoma
immunomodulators
durvalumab
  • 0 views
  • 16 Feb, 2024
  • 95 locations
Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by either pembrolizumab with olaparib placebo (Arm 1) or with olaparib (Arm 2) compared to concurrent chemoradiation therapy followed by durvalumab (Arm 3) in participants with unresectable, locally advanced …

cancer
immunomodulators
lung cancer
pemetrexed
durvalumab
  • 0 views
  • 16 Feb, 2024
  • 14 locations
177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours

This is a phase I study of 177Lu-DOTA-TATE in combination with the PARP-inhibitor olaparib for treatment of patients with somatostatin receptor positive tumours detected by 68Ga-DOTA-TATE/TOC PET. The combination of a PARP inhibitor that will specifically target the repair mechanism, with ionising radiation causing SSB's might overcome the repair dependent …

complete resection
bilateral oophorectomy
hormone levels
ki-67
progressive disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
Delayed Initiation of Olaparib Maintenance Therapy in Platinum Sensitive Recurrent Ovarian Cancer

The purpose of this study is to test if delaying the start of the olaparib until there is a rise in a tumor marker called CA-125 will result in a longer time until the next or different treatment for the patient's cancer.

cancer antigen 125
maintenance therapy
peritoneal cancer
recurrent ovarian cancer
neutrophil count
  • 0 views
  • 05 Aug, 2020