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Found 2 clinical trials
Zanubrutinib Ixazomib and Dexamethasone in Patients With Treatment Naive Waldenstrom's Macroglobulinemia

We propose this combination will improve the deep remission (VGPR) compared to single Zanubrutinib or IRD regimen and can be a time-limited regimen which will reduce the life-time therapy and benefit the patients.

night sweats
indolent lymphoma
treatment regimen
neutrophil count
neuropathy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Brief Title: Study of BGB-10188 as Monotherapy and in Combination With Zanubrutinib and Tislelizumab

The purpose of this study is to determine the maximum tolerated dose (MTD), recommended Phase 2 dose(RP2D),safety & tolerability of BGB-10188: as monotherapy in participants with mature B-cell malignancies; oin combination with zanubrutinib in participants with relapse/refractory follicular lymphoma (R/R FL), mantle cell lymphoma (MCL) or diffuse large B-cell lymphoma …

microsatellite instability high
esophageal cancer
cancer of the ovary
transitional cell carcinoma
systemic therapy
  • 0 views
  • 16 Feb, 2024
  • 4 locations