Found 12 clinical trials
Determination of the Optimal Treatment Target in Ulcerative Colitis
Disease activity and response to therapy in ulcerative colitis (UC) can be assessed by a range of endpoints including symptoms, endoscopic mucosal activity, histological disease activity, and biomarkers.
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- 16 Feb, 2024
- 1 location
MicroNet-covered Stent System for Stroke Prevention in All Comer Carotid Revascularization
All-comer study of unselected patients suitable for carotid artery revascularization to evaluate the feasibility, efficacy and safety of first line endovascular revasculariztion using MicroNet covered stent (CGuard) in the treatment of consecutive symptomatic and increased-stroke-risk asymptomatic carotid lesions that require revascularization by Neurovascular Team decision.
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- 16 Feb, 2024
- 1 location
Less Infections for the Diabetic Foot
This is a randomized, unblinded, single-centre study. After eventual surgical debridement (not amputation), patients will be randomized to receive 1 of 2 targeted antibiotic regimens, in the ratio 1:1. For diabetic toe osteomyelitis, the patients will be randomized between a 3 and a 6 week's arm, for soft tissue infections …
- 0 views
- 16 Feb, 2024
- 1 location
Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis (TOP-N53-02)
The main goal of this clinical trial is to learn about how safe the new drug TOP-N53 solution is when it is applied to open wounds on the fingertip (digital ulcers) in people with an uncommon illness that results in hard, thickened areas of skin and additional problems with internal …
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- 02 May, 2025
Boosting Biologics in UC
The project will explore whether probiotics have beneficial effects as adjuvant therapy in ulcerative colitis patients with insufficient response to anti-TNF treatment.
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- 16 Feb, 2024
- 1 location
Implementation of Telemedicine for Patient With Lower Extremity Wounds
The objective of this study is to determine if patients with lower extremity wounds in rural communities who undergo specialty referral through telemedicine have expedited care compared to patients who are treated through standard in person referral.
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- 05 Aug, 2020
Neoadjuvant T-VEC in High Risk Early Melanoma
Survival remains significantly poorer for thicker and ulcerated lesions with T3b and T4 lesions demonstrating less than 50% survival at 5 years independent of other prognostic indicators. Oncolytic viral therapies (OVT) stimulate or suppress the immune system in different ways to stop cancer cells from growing and intra-lesional OVT has …
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- 16 Feb, 2024
- 1 location
Full Metall Jacket Multilevel Segment
Hypothesis: "Total" endovascular revascularization of a multistory lesion of the iliac-femoral-popliteal segment is safer and a better quality of life is achieved in comparison with hybrid intervention. The lack of damage to the skin avoids complications in the postoperative and remote periods of observation, thereby improving the quality of life
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- 16 Feb, 2024
- 1 location
Inflammatory Bowel Disease (IBD) Research Registry
Patients seen at the Center for Inflammatory Bowel Disease will be asked to provide their written informed consent (authorization) to allow their identifiable medical record information related to their Inflammatory Bowel Disease to be placed in Center's Research Registry for the purpose of facilitating retrospective research studies directed at Inflammatory …
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- 16 Feb, 2024
- 1 location
Nutritional State and Care Pathway of Hospitalized Malnourished Patients Within 3 Months of Admission
Malnourished patients are at risk of many complications, including infections, pressure ulcers and readmissions. Little is known about their care pathway after hospital discharge. This study aims to determine care pathways of malnourished patients after hospital discharge and to determine what they need to better take care of their malnutrition.
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- 16 Feb, 2024
- 1 location
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