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Found 3 clinical trials
Tofacitinib for Treatment of Moderate COVID-19

The purpose of this randomized, double blinded, placebo controlled study is to assess the efficacy and safety of tofacitinib in hospitalized adult (18-65 years old) patients with SARS-CoV-2 and pneumonia who require supplemental oxygen and have serologic markers of inflammation but do not need mechanical ventilation.

coronavirus infection
covid-19
acute respiratory syndrome (sars)
PCR test
mechanical ventilation
  • 0 views
  • 05 Aug, 2020
Tofacitinib for Immune Skin Conditions in Down Syndrome

The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug known to block IFN signaling, in adults with DS and an autoimmune and/or autoinflammatory skin condition.

disseminated herpes simplex
atopic dermatitis
skin disorder
alopecia areata
eczema
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms

The study is a prospective, randomized, controlled investigation designed for comparison of two groups for the reduction of respiratory distress in a CoViD-19 population, using gammaCore Sapphire (nVNS) plus standard of care (active) vs. standard of care alone (SoC), the control group. The gammaCore (nVNS) treatments will be used acutely …

oximetry
dyspnea
vagus nerve stimulation
oxygen saturation
covid-19
  • 0 views
  • 16 Feb, 2024
  • 1 location