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Found 2 clinical trials
Study in Subjects With Relapsed/Refractory Follicular Lymphoma

This is a multicenter, double-blind, active-controlled, randomized, 3-stage, biomarker enrichment design featuring early futility stopping and sample-size re-estimation with safety run-in designed to evaluate the efficacy and safety of tazemetostat in combination with R2 in subjects with R/R FL, who have completed at least 1 prior systemic chemotherapy, immunotherapy, or …

investigational treatment
hepatitis b surface antigen
cancer therapy
bone marrow procedure
total body irradiation
  • 0 views
  • 16 Feb, 2024
  • 8 locations
A Study of Oral Tazemetostat in Subjects With Moderate and Severe Hepatic Impairment With Advanced Malignancies

This is a phase 1, 2-part, global, multicenter, open-label, PK, safety and tolerability study of oral tazemetostat in subjects with either advanced solid tumors, or hematological malignancies and normal hepatic function or moderate, or severe hepatic impairment.

serum pregnancy test
hepatic impairment
cervical cancer
hemolysis
sarcoma
  • 0 views
  • 16 Feb, 2024
  • 5 locations