Found 6 clinical trials
Comparison of Eligible TAVI-valves - Cohort B
The study performs head-to-head comparison of two TAVI-valves: Sapien and Myval.
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- 05 Aug, 2020
Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI
Study population: Approximately 80 patients with severe symptomatic aortic valve stenosis with an indication for TAVI will be included. Intervention: Patients will undergo cardiac MRI on top of standard clinical care within 30 days after TAVI.
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- 16 Feb, 2024
- 1 location
Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis (CHOICE-FR)
The purpose of the current study is to assess complete coronary physiology (FFR, RFR, CFR, IMR, and CT-FFR) in TAVI candidates with intermediate coronary artery stenosis before and 6 months after TAVI. This aims to determine how TAVI affects coronary blood flow and coronary microcirculatory function after longer-term follow-up, and …
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- 29 Nov, 2021
- 1 location
Hamburg AoRtic Valve cOhoRt
The primary aim of the study is to identify the optimal treatment modality for patients with aortic valve disease, incorporating the individual patient's risk profile and anticipated clinical outcomes. This includes the association of demographic factors, procedural data and biomarkers with clinical outcome in a prospective fashion.
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- 16 Feb, 2024
- 1 location
Cardiac Output, Cerebral Perfusion and Cognition in Patients With Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation (CAPITA)
Cognitive impairment is common (21-39%) among patients with severe aortic valve stenosis. The proof-of-concept CP-TAVI study showed that increased cardiac output following transcatheter aortic valve implantation (TAVI) was associated with increased cerebral blood flow.
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- 11 Jan, 2023
- 1 location
COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis.
Subsequently, when these patients undergo a post-intervention (whether SAVR or TAVI) evaluation 6 months after valve replacement, the effect of valve replacement on FFR, RFR and IMR will be determined.
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- 16 Feb, 2024
- 1 location