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Found 3 clinical trials
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

The goal of this research proposal is to clinically validate an innovative precision medicine strategy for dosing the immunosuppressant tacrolimus in pediatric heart transplant, which will in turn lead to improvements in long-term transplant survival outcomes. The strategy and techniques used in this project can be extended to improve drug …

  • 0 views
  • 16 Feb, 2024
  • 2 locations
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function

Tacrolimus is the standard immunosuppressive drug used to prevent organ rejection post liver transplant. One side effect of Tacrolimus is nephrotoxicity.

nephrotoxicity
immunosuppression
liver transplant
anti-thymocyte globulin
everolimus
  • 0 views
  • 16 Feb, 2024
  • 1 location
Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

This phase II trial studies how well total marrow and lymphoid irradiation works as a conditioning regimen before hematopoietic cell transplantation in patients with myelodysplastic syndrome or acute leukemia. Total body irradiation can lower the relapse rate but has some fatal side effects such as irreversible damage to normal internal …

white blood cell count
hepatitis b core antibody
hepatitis b surface antigen
transplant conditioning
etoposide
  • 0 views
  • 16 Feb, 2024
  • 1 location