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Found 3 clinical trials
Pyrotinib Trastuzumab Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer

This study aims to evaluate the efficacy and safety of pyrotinib in combination with trastuzumab, pertuzumab and nab-paclitaxel as neoadjuvant therapy in early stage or locally advanced HER2-positive breast cancer.

her2 positive breast carcinoma
erbb2 gene amplification
gene amplification
estrogen receptor
estrogen
  • 0 views
  • 16 Feb, 2024
  • 1 location
Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

This study is a one-arm, open, phase II clinical study, and the study subjects are locally advanced and inflammatoryPatients with sexual or early HER2-positive breast cancer entered the trial period after signing informed consentTo evaluate trastuzumab combined with pyrrolitinib and chemotherapy regimen (TCbH+Py) for HER2 positive breastPathologic complete response rate …

primary lesion
targeted therapy
invasive breast cancer
bisphosphonate therapy
trastuzumab
  • 0 views
  • 16 Feb, 2024
  • 1 location
An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC.

This is a Phase II, open-label, randomized controlled umbrella trial evaluating the efficacy and safety of multiple targeted treatment in patients with metastaticTNBC.

solid tumour
stage iv breast cancer
everolimus
capecitabine
measurable disease
  • 0 views
  • 16 Feb, 2024
  • 1 location