Found 8 clinical trials
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant
The goal of this research proposal is to clinically validate an innovative precision medicine strategy for dosing the immunosuppressant tacrolimus in pediatric heart transplant, which will in turn lead to improvements in long-term transplant survival outcomes.
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- 16 Feb, 2024
- 2 locations
Precision Medicine for Nociception, Sngception and Proprioception.
Precision medicine is defined as "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person" by the Precision Medicine Initiative.
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- 08 Dec, 2023
Development of Systems and Precision Medicine - Take Mood Disorder as an Example.
Precision medicine is to achieve individual optimal health care, given the biological mechanisms, genetic variants, and environmental measurements.
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- 16 Feb, 2024
- 1 location
Off-label Use of Anti-cancer Drugs in Norway -a Prospective Cohort Study
The number of drugs suitable for off-label use is expected to further increase in the coming years, owing to the rapid progress in the field of oncology, in particular with the current era of precision medicine and targeted therapies. This also challenges the traditional method of running clinical trials, with …
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- 05 Aug, 2020
Advanced Translational Research on Childhood Leukemia
Prognosis of children with leukemia, the most common pediatric cancer, has improved markedly. Yet, relapse still occurs in 15-40% of patients with a probability of survival of <50%, which is unlikely to be boosted by intensification of standard chemotherapy due to overwhelming toxicity. The advent of effective and safe targeted …
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- 05 Aug, 2020
PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies
We will collect clinical data, biological samples and imaging results in order to perform future cross-sectional studies and/or longitudinal studies for elucidating pathways of the disease and develop and validate biomarkers for diagnosis, prognosis and monitoring liver disease and comorbidities in order to contribute to precision medicine in this field.
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- 16 Feb, 2024
- 1 location
The Harefield Acute Myocardial Infarction Cohort
In this project the investigator's plan to collect blood during a patient's routine angiogram procedure which they will have due to having suffered a heart attack. Data from the patients' routine procedures for this condition, including but not exclusively, ECG, Echocardiogram, MRI scans, will be collected. The aim of the …
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- 16 Feb, 2024
- 2 locations
Impact of the Comprehensive Geriatric Assessment on the Quality of Life OF Elderly Patients
Impact of the Comprehensive Geriatric Assessment on the Quality of Life of elderly onco-hematologic patients' candidates for complex antitumoral therapies: clinical and biological correlatives
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- 05 Aug, 2020