Found 7 clinical trials
Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose (Optimal Bup)
The investigators aim to test the effectiveness of a high maintenance daily dose of buprenorphine (24 mg) for improving outcomes among patients who used fentanyl compared to the standard daily dose (16 mg).The main question it aims to answer is: will patients who are randomly assigned to the high 24 …
- 0 views
- 22 Apr, 2024
- 1 location
Treatment of Pregnant Women With OUD
The investigators are testing two models of support for pregnant women with an opioid use disorder (OUD)
- 0 views
- 16 Feb, 2024
- 12 locations
The Effect of Chronic Pain on Delay Discounting in Methadone Patients
Medication assisted treatment, including methadone and buprenorphine, is the standard of care for the treatment of opioid use disorder (OUD). However, chronic pain can reduce treatment efficacy during medication assisted treatment and is associated with illicit substance relapse, dropout, and subsequent overdose.
- 0 views
- 16 Feb, 2024
- 1 location
Optimization of NIBS for Treatment of Addiction
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial …
- 0 views
- 16 Feb, 2024
- 1 location
INDV-2000 First in Human
This study will be a single ascending dose (SAD) study conducted to identify the maximum tolerated dose (MTD). After completion of the SAD portion of the study and acceptable safety evaluation, a food-interaction, single-dose study under fed and fasted conditions will be conducted.
- 0 views
- 16 Feb, 2024
- 1 location
Intervening With Opioid-Dependent MothersMothers and Infants
This study will assess the efficacy of the modified Attachment and Biobehavioral Catch-Up (mABC) Intervention, adapted for use with peripartum mothers receiving medication-assisted treatment for opioid use disorder. The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and …
- 0 views
- 16 Feb, 2024
- 1 location
myoActivation for Chronic Pain in a Marginalized Population
Marginalized populations are at increased risk of chronic pain, trauma and use of street drugs to manage this suffering, with the associated risk of overdoses. Non-pharmacological options to manage chronic pain are difficult for this population to access. myoActivation is an innovative structured assessment and therapeutic approach. This study will …
- 0 views
- 16 Feb, 2024
- 1 location