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Found 3 clinical trials
A Clinical Trial to Evaluate the Effect of Nilotinib on the PK/PD of Meformin

The aim of the study is to evaluate the effect of nilotinib on the pharmacokinetics and pharmacodynamics of metformin in healthy male adults

body mass index
metformin
  • 0 views
  • 05 Aug, 2020
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Participants will repeat the screening tests during the study. Participants will receive nilotinib and paclitaxel. The drugs are given in 28-day cycles. Nilotinib is a capsule taken by mouth twice a day. Paclitaxel will be given intravenously by peripheral line or central line once a week for the first 3 …

urine test
mitomycin
sarcoma
transitional cell carcinoma
cholangiocarcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease.

This study aims to determine if one of three low doses of lithium therapy for 6 months can engage one or more blood-based therapeutic targets implicated in Parkinson's disease (PD) pathophysiology. Results of this study will help to determine if lithium therapy is worthwhile to further investigate as a potential …

arrhythmia
nilotinib
brain stimulation
dementia
antidepressants
  • 0 views
  • 16 Feb, 2024
  • 1 location