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Found 86 clinical trials
  • 0 views
  • 18 Nov, 2024
Featured trial
Fatty Liver  

Fatty liver disease (FLD), also known as hepatic steatosis, is a condition where excess fat builds up in the liver.

cancer
hepatitis c
  • 0 views
  • 14 Mar, 2022
  • 1 location
Featured trial
Precise Profiling of Liver Disease Patients With DPMAS Therapy, Treating Optimal Patients and Achieving Hard Endpoint (PADSTONE Study) (PADSTONE)

Acute-on-chronic liver failure (ACLF) is life-threaten syndrome in patients with chronic liver disease. In China, hepatitis B virus (HBV) is the main etiology of cirrhosis and HBV-ACLF is characterized by multiple organs failure (liver, coagulation and kidney, etc.)

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  • 23 Nov, 2021
  • 1 location
DUR-928 in Subjects With SARS-CoV-2 With Acute Liver or Kidney Injury

Evaluate safety and efficacy of DUR-928 in treatment of acute organ failure in subjects infected with SARS-CoV-2

kidney injury
liver disease
SARS
organ failure
acute respiratory syndrome (sars)
  • 0 views
  • 01 Feb, 2023
Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Hilar Cholangiocarcinoma. A Prospective Multicenter Study.

A prospective multicentre pilot study which includes patients 70 years-old diagnosed of unresectable hilar cholangiocarcinoma (hCCA) 3cm in radial diameter, without evidence of lymph node or distant metastases. Liver transplantation preceded by neoadjuvant radio-chemotherapy will be performed in this selected group. The primary endpoint will be overall survival at 1, …

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  • 16 Feb, 2024
  • 1 location
A Randomized Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Proven NASH

A randomized, double-blind study to assess the safety and efficacy of EDP-305 in subjects with liver-biopsy proven Non-Alcoholic Steatohepatitis (NASH)

fibrosis
body mass index
hcv infection
HIV Infection
hepatitis b surface antigen
  • 0 views
  • 05 Aug, 2020
PHP and Immunotherapy in Metastasized UM

Melphalan will be administered selectively to the liver via percutaneous hepatic perfusion, limiting the systemic effect of chemotherapy. With this treatment combination we aim to find a treatment for disseminated uveal melanoma, both in the liver as in the other organs.

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  • 16 Feb, 2024
  • 1 location
Pharmacokinetics and Safety of SHR0302 in Patients With Hepatic Impairment

Study to Evaluate Pharmacokinetics and Safety of SHR0302 in Patients With Mild, Moderate Hepatic Impairment and Normal Liver Function in Phase I Clinical Study

hepatic impairment
moderate hepatic impairment
body mass index
liver disease
moderate hepatic insufficiency
  • 0 views
  • 16 Feb, 2024
  • 1 location
Vitamin K Supplementation Study in Healthy Volunteers (Aim 2B)

We propose that the CYP4F23 gene variant increases short- and long-term vitamin K concentrations in the liver by reducing the efficiency of vitamin K metabolism. The investigators will study the effect of vitamin K supplementation on two biomarkers of hepatic vitamin K concentration in groups with defined CYP4F23 genotype.

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  • 05 Aug, 2020
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Eligibility People ages 2 and older with DBA who did not respond to steroids or could not take them, or their disease has returned despite taking them Design Participants will be screened with: Medical and medicine history Physical exam MRI: Participants will lie in a machine that takes pictures of …

bone marrow biopsy
corticosteroids
blood cell count
blood transfusion
anemia
  • 0 views
  • 16 Feb, 2024
  • 1 location