Found 2 clinical trials
Multiomics After Headache Provocation of People Who Are Unable to Have Headache
The investigators will measure multiomic changes (transcriptomics and metabolomics) after headache provocation with isosorbide mononitrate. 3 blood samples, two for RNA and one for metabolomics are taken right before administration of isosorbide mononitrate, 3 hours after administration of isosorbide mononitrate and again 5 hours after administration of isosorbide mononitrate.
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- 16 Feb, 2024
- 1 location
Headache Provocation of People Who Are Unable to Have Headache
The aim of the study is to identify factors that protect against headache by studying headache after provocation in people who never have had a headache (headache resistant) versus non-resistant controls. The investigators will use isosorbide mononitrate as a pharmacological trigger of headache. The provocation is performed by investigators who …
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- 16 Feb, 2024
- 1 location