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Found 15 clinical trials
Unacylated Ghrelin to Improve Functioning in PAD

GIFT is a pilot, randomized, double-blinded clinical trial that will examine the effects of unacylated ghrelin on walking ability in people with peripheral artery disease (PAD) compared to placebo. Preliminary evidence suggests that unacylated ghrelin may improve blood flow to the extremities and promote improved skeletal muscle growth and energy …

ghrelin
peripheral arterial diseases
peripheral artery disease
arteriopathy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effects of Age and Obesity on Brain Insulin Sensitivity

In this context, the overall aim is to study brain insulin resistance to disentangle age-related and obesity related brain insulin resistance in healthy normal and overweight/obese persons at the age of 20 to 70 years .

glucose tolerance test
tolerance test
MRI
functional mri
oral glucose tolerance test
  • 0 views
  • 05 Aug, 2020
PCOS Treatment Using DLBS3233, Metformin, and Combination of Both (POSITIF)  

This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over 6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety of DLBS3233 alone, metformin and combination of both, in improving metabolic and reproductive parameters.

  • 0 views
  • 26 Oct, 2022
  • 4 locations
PCOS Treatment Using DLBS3233 and Metformin.

This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over 6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety of DLBS3233 alone, metformin and combination of both, in improving metabolic and reproductive parameters.

  • 0 views
  • 23 Sep, 2022
  • 3 locations
TEST SITE

This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over 6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety of DLBS3233 alone, metformin and combination of both, in improving metabolic and reproductive parameters.

  • 0 views
  • 28 Sep, 2022
  • 3 locations
Study Site

This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over 6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety of DLBS3233 alone, metformin and combination of both, in improving metabolic and reproductive parameters.

  • 0 views
  • 28 Sep, 2022
Test

This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over 6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety of DLBS3233 alone, metformin and combination of both, in improving metabolic and reproductive parameters.

  • 0 views
  • 26 Sep, 2022
  • 3 locations
Study Test Site  

This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over 6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety of DLBS3233 alone, metformin and combination of both, in improving metabolic and reproductive parameters.

  • 0 views
  • 28 Sep, 2022
  • 2 locations
Improving Insulin Sensitivity by Non-invasive Brain Stimulation

Furthermore, the project will provide the unique opportunity to investigate novel mechanisms of insulin resistance in participants who have been extensively metabolically characterized.

obesity
MRI
insulin sensitivity
insulin
type 2 diabetes mellitus
  • 0 views
  • 16 Feb, 2024
  • 1 location
Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging

Aging is the number one risk factor for the majority of chronic diseases. There are no pharmaceutical treatments to slow aging and prolong healthspan. The anti-diabetic drug metformin is considered a likely pharmaceutical candidate to slow aging. In this study, the investigators hypothesize that metformin treatment in subjects free of …

muscle biopsy
a 12
insulin sensitivity
chronic disease
metformin
  • 0 views
  • 16 Feb, 2024
  • 2 locations