Found 68 clinical trials
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- 04 Aug, 2023
- 1 location
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension
The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.
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- 16 Feb, 2024
- 211 locations
Therapeutic Adherence in Uncontrolled Arterial Hypertension
Resistant arterial hypertension, together with difficult-to-control hypertension, has a worse cardiovascular prognosis than controlled hypertension. In addition, data on therapeutic adherence in arterial hypertension show that 1 in 2 hypertensive patients do not fully or partially comply with the indicated therapeutic prescription.
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- 16 Feb, 2024
- 1 location
PMCs as a Treatment of Children With HSPM Using the HT
Hypomineralised primary second molars are primary molars with a developmental disorder of the enamel. Preformed metal crowns already have good results for the treatment of caries on primary molars. In this study the aim is to investigate the clinical success and overall survival of preformed metal crowns as a treatment …
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- 16 Feb, 2024
- 1 location
Clinical Trial of YuWell YE900 Electronic Sphygmomanometer
The purpose of this study is to evaluate the accuracy of the YuWell YE900 medical electronic blood pressure monitor for blood pressure measurements in adults and children according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Universal Standard (ISO 81060-2:2018).
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- 05 Aug, 2020
Inhaled Nitric Oxide for Preventing Progression in COVID-19
This is a pilot randomized-controlled (2:1) open label investigation of inhaled NO to prevent progression to more advanced disease in 42 hospitalized patients with COVID-19, at risk for worsening, based on baseline systemic oxygenation and 2 or more of the major risk factors of age > 60 years, type II …
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- 05 Aug, 2020
Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19)
The objectives of this study are to evaluate the safety, tolerability and efficacy of AT-527 in older subjects (ages 45-80 years) with moderate COVID-19 and risk factors for poor outcomes (such as obesity (BMI>30), hypertension, diabetes or asthma). Eligible subjects will be randomized to blinded AT-527 (nucleotide analog) tablets or …
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- 16 Feb, 2024
- 10 locations
403 trial & test1
Participants will receive a stipend of $50 for participating. You must not have scleroderma, pulmonary hypertension, diseases with similarities to scleroderma (including myositis, lupus, Sjogren’s syndrome, or rheumatoid arthritis), or other conditions that affect your immune system.
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- 28 Apr, 2025
Relation Between Mean Arterial Pressure and Renal Resistive Index in the Early Phase of Septic Shock
This study evaluates if improvement of renal resistive index when mean arterial pressure increase (at 65 mmHg to 85 mmHg) in early phase of septic shock is predictive of better renal survival.
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- 16 Feb, 2024
- 1 location
Cyclosporine in Patients With Moderate COVID-19
Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.
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- 16 Feb, 2024
- 1 location