Found 14 clinical trials
Consequences of a Maternal-fetal Chikungunya Virus Infection
During neurodevelopmental monitoring, other disturbing traits complemented the spectrum of problems presented by these children, such as microcephaly, cerebral palsy, epilepsy, interaction disorder or attention deficit disorder. At around age 10, we reassessed 21 of these children using the Childhood Cognitive Function and Learning (EDA) screening test.
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- 14 Mar, 2022
- 2 locations
Bridging the Childhood Epilepsy Treatment Gap in Africa
About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs).
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- 16 Feb, 2024
- 3 locations
Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study (TOPAMAD)
This study has been planned to compare the efficacy and tolerability of topiramate, a commonly used second line agent, with modified Atkins diet in children with epileptic spasms refractory to hormonal treatment, in a randomized open label study.
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- 25 Jul, 2023
- 1 location
Using Direct Brain Stimulation to Study Cognitive Electrophysiology
This project forms a multi-site research collaboration to carry out verbal and spatial memory experiments in patient volunteers to better understand the neural bases of human memory, employing direct electrical brain stimulation as a tool to study those dynamics and their relationship to memory performance.
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- 16 Feb, 2024
- 6 locations
Pilot Trial to Evaluate The Effect of Oral Methylprednisolone on Seizure Frequency in Children With Epilepsy
Although corticosteroids have been shown to be beneficial anecdotally for refractory epilepsy, the effects of corticosteroids on pediatric epilepsy have primarily been studied retrospectively amongst a heterogeneous patient population.
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- 16 Feb, 2024
- 1 location
An Open-Label Study to Investigate the Safety of Single Ascending Doses in Children and Adolescents With Dravet Syndrome
Stoke Therapeutics is evaluating the safety and tolerability of single ascending doses of STK-001 in patients with Dravet syndrome. Change in seizure frequency and quality of life will be measured as secondary endpoints in this open-label study.
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- 05 Aug, 2020
Anterior Temporal Lobectomy in Temporal Glioblastoma (ATLAS/NOA-29)
ATL offers a reproducible supramarginal resection approach within anatomical boundaries that are routinely respected in epilepsy surgery.Patients are randomized intraoperatively in a 1:1 ratio following histopathological confirmation via intraoperative frozen section procedure.
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- 14 Jun, 2025
XLTCS - Accelerometer Data Collection in an Epilepsy Monitoring Unit (EMU)
The primary objective of this study is to collect accelerometer data from subjects monitored in an EMU with concurrent video EEG.
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- 16 Feb, 2024
- 1 location
European Non-interventional Study on Refractory Epilepsy With Developmental Delay.
This is a multinational, multicentre, non-interventional, retrospective data collection (manual Medical Chart Review).
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- 05 Aug, 2020
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