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Found 26 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

mini-mental state examination
apolipoprotein e4
alzheimer's disease
mental state examination
  • 32 views
  • 16 Feb, 2024
  • 127 locations
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

They will visit NIH 6 months after treatment ends. If participants blood counts go down after treatment ends, they may restart the drug....

bone marrow biopsy
eltrombopag
anemia
blood transfusion
electrocardiogram
  • 0 views
  • 16 Feb, 2024
  • 1 location
Group Activities to Support Addiction Recovery

HB is the practice of self-directed hyperventilation while lying down with the support of a selected music set and trained facilitators. Participants may experience an expanded state of consciousness with altered cognition, perception, and emotions.

  • 0 views
  • 25 Jul, 2025
  • 1 location
Baseline Relative Peripheral Refraction in Myopia Control

Myopia has become a world concern and its prevalence has increased in recent decades. Myopic defocus has been applied for slowing down the axial elongation and myopia progression, which is mainly based on the theory of simultaneous competing defocus and peripheral optics.

Accepts healthy volunteers
  • 0 views
  • 08 Dec, 2023
  • 1 location
Oral Oxytocin's Effects on Attention Control

The main aim of the study is to investigate whether orally administered oxytocin (24IU) could modulate attention control using a social-emotional saccade/antisaccade eye-tracking paradigm.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Tofacitinib for Immune Skin Conditions in Down Syndrome

People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions.

atopic diathesis
down syndrome
skin disorder
disseminated herpes simplex
eczema
  • 0 views
  • 16 Feb, 2024
  • 1 location
As-needed Budesonide/Formoterol Turbuhaler in Stepping Down Period

This study will evaluate the efficacy of as-needed Budesonide/formoterol Turbuhaler 160/4.5 g/d in the period of step down in well controlled asthmatic patient comparing with standard maintenance therapy in step-2 management in asthma guildeline which is low dose inhaled corticosteroid.

theophylline
montelukast
fractional exhaled nitric oxide
maintenance therapy
eosinophil count
  • 0 views
  • 16 Feb, 2024
  • 1 location
Human Umbilical Cord Mesenchymal Stem Cells For the Treatment of Lumbar Disc Degeneration Disease

We hypothesize grafting hUCMSC into the degenerative disc leads to symptoms relief and slow down the progression of disc degeneration.

morphine
lumbar disc herniation
manipulative therapy
back pain
lumbar disc degeneration
  • 0 views
  • 16 Feb, 2024
  • 1 location
Antioxidant-rich Diet and Oxidative Stress in Healthy Preschoolers

Given that many diseases can start as early as childhood, eating patterns in childhood and preventing oxidative damage can have beneficial long-term health effects. Antioxidant-rich foods can slow down the progression of chronic diseases. In Slovenian kindergartens (and schools) children consume up to 70% of their daily energy and nutritional …

diabetes
antioxidants
hyperlipidemia
cancer
cardiovascular disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
An Open Label Study of FT218 in Subjects With Narcolepsy

An Open Label Study to Evaluate Long-Term Safety and Tolerability of a Once Nightly Formulation of Sodium Oxybate for Extended-Release Oral Suspension (FT218) and the ability to switch from twice-nightly immediate release sodium oxybate to once-nightly FT218 for the Treatment of Excessive Daytime Sleepiness and Cataplexy in Subjects with Narcolepsy

excessive daytime sleepiness
cataplexy
somnolence
narcolepsy
sleepiness
  • 0 views
  • 05 Aug, 2020