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Found 4 clinical trials
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

This phase II trial studies how well liposome-encapsulated daunorubicin-cytarabine (CPX-351) works in treating patients with secondary acute myeloid leukemia who are younger than 60 years old. Drugs used in chemotherapy, such as CPX-351, work in different ways to stop the growth of cancer cells, either by killing the cells, by …

secondary acute myeloid leukemia
acute myeloid leukemia with myelodysplasia-related changes
daunorubicin
chronic myelomonocytic leukemia
treatment related acute myeloid leukemia
  • 0 views
  • 16 Feb, 2024
  • 1 location
CPX-351 in Higher Risk Myelodysplastic Syndromes

Study of the efficacy of CPX-351 treatment in patients with higher risk myelodysplastic syndromes : as first line treatment or after hypomethylating agents failure

chronic myelomonocytic leukemia
nephropathy
myelodysplastic syndrome
platelet transfusion
direct bilirubin
  • 0 views
  • 16 Feb, 2024
  • 12 locations
The Acute Promyelocytic Leukaemia Asian Consortium (APL-AC) Project

There is currently lack of collaborative data on the epidemiology, clinicopathologic features and treatment outcome of newly diagnosed and relapsed APL in Asia. In addition, there is lack of data comparing oral- As2O3-based regimens with other treatment approaches, including intravenous As2O3,in the frontline or relapsed setting. With the long-term data …

acute promyelocytic leukemia
leukemia
acute myeloid leukemia
rara translocation
arsenic
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cancer Therapy Effects on the Heart

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death.

daunorubicin
MRI
childhood cancer
metastasis
anthracyclines
  • 0 views
  • 16 Feb, 2024
  • 1 location