crizotinib Clinical Research Trials

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Found 3 clinical trials

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Phase 2
For pediatric ages
For Seniors
Recruiting in 10s
Interventional Study
all
Genetic Disease
Recruiting

Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

cataract

nf2 gene

crizotinib

schwartz

neurofibroma

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16 Feb, 2024
17 locations

Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Family Medicine
Recruiting

Lorlatinib Combinations in Lung Cancer

This research study involves three study drugs. Lorlatinib Binimetinib Crizotinib

kinase inhibitor therapy

cns lesion

malabsorption

major surgery

probe

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16 Feb, 2024
2 locations

Phase 2
For pediatric ages
For Seniors
Recruiting in 10s
Interventional Study
all
Neurology
Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2

This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with neurofibromatosis type 2 (NF2) with associated progressive tumors of vestibular schwannomas (VS), non-vestibular schwannomas (non-VS), meningiomas, and ependymomas. This Master Study is being conducted as a "basket" study that may allow …

cataract

ependymoma

experimental drug

experimental therapy

vasectomy

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05 Aug, 2020