Found 7 clinical trials
Minocycline in MS: Confirmation of Benefit
This is an open-label, single-arm clinical trial. Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging (MRI) with at least two brain T2 lesions which are at least 3 mm …
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- 16 Feb, 2024
- 1 location
Epidemiologic and Clinical Characteristics of Optic Neuritis in China
This will be a hospital-based retrospective multi-center study on epidemiologic and clinical characteristics of optic neuritis among Chinese. The investigation will cover about 29 provinces or municipalities all around China.
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- 16 Feb, 2024
- 1 location
Better Delineation of YY1 Related Phenotype and Epigenetic Signatures.
The aims of this study are first to better delineate the clinical phenotype, as well as the neuropsychological profile, and the brain MRI characteristics; and, second, to study the epigenetic signatures in a cohort of individuals with YY1 intragenic pathogenic variants.
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- 16 Feb, 2024
- 1 location
Local Ablative Therapy for Patients With Multiple (4-10) Brain Metastases
To observe the quality of life (QOL) and to report on toxicity and outcome parameters after the (repeated) use of local ablative therapy (LAT) i.e. stereotactic radiotherapy (SRT) for patients with multiple (4-10) brain metastases
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- 16 Feb, 2024
- 1 location
A Study of Cognitive Changes in Patients Receiving Brain Radiation
Cranial radiation therapy (RT), commonly used to treat benign and malignant brain tumors, can lead to cognitive impairments in domains not related to neuroanatomic structures directly impacted by the tumor. The study will prospectively enroll 58 patients with benign and low-grade brain tumors who will undergo partial brain RT, with …
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- 16 Feb, 2024
- 1 location
Neurodegenerative Diseases Registry
With the increase in life expectancy of our population due to advancement of medical diagnosis and treatments, the incidence of age dependent neurodegenerative diseases increased, including Alzheimer's disease (AD), parkinsonian syndromes (PS), small vessel disease (SVD) and motor neuron disease (MND). In spite of the progress of knowing the pathogenesis …
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- 05 Aug, 2020
Brain MRI in Stroke Patients With Intracardiac Thrombus
In earlier reports, infarction of cardioembolic origin has been associated with acute lesions involving the cortex, and with multiple acute lesions in single or multiple cerebral circulation territories, and small (most often chronic and asymptomatic) cortical cerebellar infarctions (SCCI). Our aim was to analyse brain MRI characteristics in patients presenting …
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- 16 Feb, 2024
- 1 location