Found 10 clinical trials
Continuous Versus Cyclical OCP Use in PCOS (CCOUP)
The mainstay treatment for females with Polycystic Ovary Syndrome (PCOS) has long been a combination of an oral contraceptive pill or OCP (containing both estrogen and progestin) along with an anti-androgen medication (such as Spironolactone) to not only prevent chronic anovulation but also suppress elevated testosterone levels and its clinical …
- 0 views
- 04 Apr, 2022
- 2 locations
Naproxen Pharmacogenetic Study (Project 1 Aim 2)
This is a mechanism-based study in healthy adults to determine the effect of the CYP2C9 M1L gene polymorphism on the functional activity of the encoded CYP2C9 enzyme towards the probe substrate naproxen. CYP2C9 activity will be evaluated by measurement of O-desmethyl naproxen and unchanged naproxen in 24-hour urine following administration …
- 0 views
- 16 Feb, 2024
- 1 location
Effects of Fish Oil and Resistance Training on Muscle Mass and Function
Following 6 weeks of FO or PLA supplementation, subjects will repeat all initial biometric, strength and neuromuscular testing, as well as a second, post-intervention blood draw.
- 0 views
- 16 Feb, 2024
- 1 location
Changes in Cellular Immune Profile During COVID-19 Infection
Clinical specimens are collected from individuals either recovered from or with active SARS-CoV-2 infection to support process and analytical development for a potential cell-based immunotherapy in preclinical research, SRPH-CVD-01. SRPH-CVD-01 is an allogeneic cell-based immunotherapy candidate to be investigated in a subsequent clinical trial under a future FDA IND to …
- 0 views
- 01 Feb, 2023
- 1 location
Lutetium-177-PSMA-I&T in Oligo-metastatic Hormone Sensitive Prostate Cancer
Radioligand therapy (RLT) using Lutetium-177 labelled PSMA is a promising new therapeutic approach to treat metastatic prostate cancer. This tumor-specific treatment is directed against prostate-specific membrane antigen (PSMA), which is overexpressed in prostate cancer cells. In the last few years, several lutetium-177 (177Lu, emitter) labeled PSMA ligands have been …
- 4 views
- 22 Aug, 2020
Long-term Consumption of Resistant Starch Type-4 (RS4)
The primary objective of the current proposal is to determine the effectiveness of long-term consumption of Fibersym RW for improving blood lipids (including cholesterol) and body composition. The overall goal of this clinical research is to determine the potential effects that RS4 consumption may have on the prevention of obesity …
- 0 views
- 16 Feb, 2024
- 1 location
Serological Surveillance for COVID-19 in Central North Carolina
For this, a nasal or throat swab will be done, or saliva will be collected. They may do this test at the same visit as the blood draw, or they may schedule an extra visit. Around the time of their study visits, participants will take an online survey about themselves, …
- 0 views
- 16 Feb, 2024
- 1 location
Antigen Presentation and Lymphocyte Response in Parkinson's Disease
The study involves a one time visit involving brief questionnaires and a blood draw of 30 mL (approximately 2 tablespoons) to be collected.
- 1784 views
- 16 Feb, 2024
- 3 locations
Early Onset Alzheimer's Disease Genomic Study
The purpose of this study is to collect samples from patients with Early-Onset Alzheimer's disease (AD) and their immediate family members for molecular analysis. Samples will be studied in order to understand how molecular changes in the body are related to the development of the disease. Researchers will study your …
- 0 views
- 16 Feb, 2024
- 1 location
Postoperative Neurocognitive Disorders
During this visit cognitive function will be assessed using the Wide Range Assessment of Memory and Learning (WRAML2) and Montreal Cognitive Assessment (MoCA) tests. Patients will also be asked to participate in a blood draw during the first 2 visits for fMRI (within five days of surgery and two days …
- 0 views
- 16 Feb, 2024
- 1 location