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Found 2 clinical trials
Decitabine With Ruxolitinib or Fedratinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms
Decitabine, with ruxolitinib or fedratinib, may work better than multi-agent chemotherapy or no pre-transplant therapy, in treating patients with accelerated/blast phase myeloproliferative neoplasms.
mds/mpd
leukapheresis
blood cell counts
myelodysplastic syndromes
hemolysis
- 0 views
- 16 Feb, 2024
- 1 location
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia"
This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orally once daily in pediatric patients with newly diagnosed chronic phase Ph+ CML (ND CML) and pediatric patients with Ph+CML who have received at least one prior TKI therapy (R/I CML), …
cml - philadelphia chromosome
karnofsky performance status
biologic agent
heart failure
chronic myeloid leukemia
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- 16 Feb, 2024
- 1 location