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Found 4 clinical trials
CCCG Relapsed Acute Lymphoblastic Leukemia 2017 Study in Children

Relapsed acute lymphoblastic leukaemia (ALL) has a poorer outcome than newly diagnosed ALL patients with only about 40% overall survival after re-treatment. The study CCCG Relapsed ALL 2017 study will adopt the UK R3 study stratification and treatment backbone with two new agents added. There will be a 4-week induction, …

bortezomib injection
flow cytometry
proteasome inhibitor
remission
cns involvement
  • 0 views
  • 16 Feb, 2024
  • 1 location
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

The BREAKFAST trial will evaluate the antitumor activity of combining cyclic fasting-mimicking diet (FMD), which reproduces the in vitro effects of glucose starvation, plus/minus metformin with standard preperative anthracycline-taxane chemotherapy in patients with stage I-III TNBC

metformin
progesterone
potassium
triple negative breast cancer
preoperative chemotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy

This study will evaluate the efficacy and safety of antharcycline-based adjuvant chemotherapy compared with observation in triple negative breast cancer (TNBC) patients with residual invasive disease after platinum and taxanes based neoadjuvant chemotherapy.

cyclophosphamide
triple negative breast cancer
breast cancer
adenocarcinoma of the breast
adenocarcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cancer Therapy Effects on the Heart

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity.

cancer therapy
anthracycline
heart failure
childhood cancer
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location