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Found 1 clinical trials
Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

After tumor hypoxia, high expression of VEGF will induce tumor cells to express programmed cell death protein-1 (PD-1), which further leads to immune escape. Targeted drugs against angiogenesis can relieve immunosuppression to a certain extent, and theoretically have a synergistic effect with anti-PD-1 immunotherapy.

growth factor
tumor angiogenesis
vascular endothelial growth factor receptor 2
apatinib
head and neck squamous cell carcinoma
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  • 05 Aug, 2020