Found 26 clinical trials
Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome
This is an open label, dose escalating safety study of the advanced therapy investigational medicinal product (ATIMP) KI-MSC-PL-205, where patients diagnosed with SARS-CoV-2-induced severe acute respiratory distress syndrome (ARDS), according to the Berlin Definition, and who are on respirator/ventilator (used synonymously in this protocol) support due to respiratory insufficiency with …
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- 05 Aug, 2020
Effect of Fibre Supplements on Gestational Diabetes (GG-GDM) : For Demo
The primary aim of this study is to evaluate the effect of a soluble fibre supplement in the development of gestational diabetes in women at high-risk. The secondary aim will to evaluate the effect of the soluble fibre supplement on glycaemic control in high-risk women who develop gestational diabetes in …
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- 07 Oct, 2022
- 3 locations
Early Use of Airway Pressure Release Ventilation (APRV) in ARDS
The investigators aim to compare APRV with conventional mechanical ventilation (MV) in patients with acute respiratory distress syndrome (ARDS).
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- 16 Feb, 2024
- 1 location
Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19
The aim of the present study is to evaluate the efficacy and safety of JAK inhibitor ruxolitinib in patients with acute respiratory distress syndrome due to COVID-19.
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- 16 Feb, 2024
- 1 location
Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients
In the intensive care unit (ICU), acute RVF is mainly due to the acute respiratory distress syndrome (ARDS), sepsis or septic shock, and less often to severe pulmonary embolism or RV infarction. The anatomical complexity of the RV precludes any geometrical assumption to estimate its volume, hence its ejection fraction …
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- 16 Feb, 2024
- 2 locations
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms
The study is a prospective, randomized, controlled investigation designed for comparison of two groups for the reduction of respiratory distress in a CoViD-19 population, using gammaCore Sapphire (nVNS) plus standard of care (active) vs. standard of care alone (SoC), the control group. The gammaCore (nVNS) treatments will be used acutely …
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- 16 Feb, 2024
- 1 location
A Longitudinal Study of COVID-19 Sequelae and Immunity
Background COVID-19 is a disease caused by the SARS-CoV-2 virus. It infects the respiratory tract. Some people who get COVID-19 have only mild symptoms. But for others, infection leads to pneumonia, respiratory failure, and, in some cases, death. Researchers want to learn more about any effects that may persist after …
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- 16 Feb, 2024
- 1 location
COVID-19: Study of INFLAmmasome and PLAtelets Functions
COVID-19 pandemic is a severe viral sepsis characterized by the occurrence of Acute respiratory distress syndrome (ARDS) whose pathophysiology is little described
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- 05 Aug, 2020
Leptospirosis Registry Gathers Knowledge on Epidemiology Clinical Course Prognostic Factors and Molecular Characteristics for Invasive Leptospirosis Disease
Incidence of invasive leptospirosis disease causing acute kidney injury, acute respiratory distress syndrome (ARDS), myocarditis, hepatic dysfunction, hemorrhage and multi-organ failure, is globally increasing and there have been frequent outbreak situation throughout the world.
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- 16 Feb, 2024
- 1 location
Immune Response and Risk of Serious Infection to SARS-Cov2
This infection is very heterogeneous in nature, ranging from asymptomatic forms to acute respiratory distress syndrome patterns in 6.1% of cases, leading to an estimated overall mortality of 5.2%. Apart from age, few risk factors for a pejorative evolution have been identified: arterial hypertension, diabetes, cardiovascular history, obesity and chronic …
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- 16 Feb, 2024
- 1 location