Found 1007 clinical trials
Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose (Optimal Bup)
The main question it aims to answer is: will patients who are randomly assigned to the high 24 mg maintenance dose, as compared to patients randomly assigned to the standard 16 mg maintenance dose, have improved retention in buprenorphine treatment (primary outcome), decreased use of non-prescribed opioids (secondary outcome), decreased …
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- 22 Apr, 2024
- 1 location
Treatment of Pregnant Women With OUD
The investigators are testing two models of support for pregnant women with an opioid use disorder (OUD)
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- 16 Feb, 2024
- 12 locations
Lap-assisted vs. US-Guided Visualization of TAP Blocks
Peripheral nerve blocks have been effective in decreasing post-operative pain as well as the use of narcotics for numerous years. Typically, these blocks are placed by anesthesiologist via ultrasound. In more recent years, surgeons have been placing nerve blocks laparoscopically. Since there are few studies that looks compare the two …
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- 16 Feb, 2024
- 1 location
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality …
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- 06 Jul, 2023
- 1 location
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality …
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- 25 Aug, 2023
- 1 location
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients
Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …
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- 16 Feb, 2024
- 1 location
The Impact of Low Pressure Pneumo in RARP II
The purpose of this study is to evaluate clinical significance of low pressure pneumoperitoneum during robotically assisted radical prostatectomy (RARP).
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- 05 Aug, 2020
Sleep Disordered Breathing With Opioid Use (SDB)
We will study additional clinical parameters like quality of life, sleep and pain in patients with and without opioid use. This proposal will enhance the investigators' understanding of the pathways that contribute to the development of sleep apnea with opioid use.
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- 01 Feb, 2023
- 1 location
Intervening With Opioid-Dependent MothersMothers and Infants
This study will assess the efficacy of the modified Attachment and Biobehavioral Catch-Up (mABC) Intervention, adapted for use with peripartum mothers receiving medication-assisted treatment for opioid use disorder. The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and …
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- 16 Feb, 2024
- 1 location
ESP Block VS Intrathecal Opioid After Laparoscopic Colorectal Surgery
This study is being done to compare 2 types of pain control methods and determine which is more effective postoperatively for laparoscopic colorectal surgery. Group 1 will receive an intrathecal (IT) injection in the back in which a small dose duramorph and bupivacaine will be placed into the spinal fluid. …
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- 28 Feb, 2022
- 1 location