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Found 1433 clinical trials
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma

This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent chemoradiotherapy(CCRT) combined with nimotuzumab can improve the survival rate of high-risk patients and may provide new evidence for individualized comprehensive treatment of …

concurrent radiochemotherapy
induction chemotherapy
cancer
carcinoma
egfr blocker
  • 4 views
  • 16 Feb, 2024
  • 1 location
Dexamethasone for COVID-19 Related ARDS: a Multicenter Randomized Clinical Trial

There is compelling data indicating that there is an excessive inflammatory response in some patients with COVID-19 leading them to develop ARDS that can be severe with a very poor prognosis. Many of these patients require very long mechanical ventilation times to survive, which have led to the collapse of …

respiratory distress
mechanical ventilation
covid-19
respiratory tract infection
respiratory infection
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Penehyclidine for Prevention of Nausea and Vomiting After Bimaxillary Surgery

Postoperative nausea and vomiting (PONV) is a common complication after surgery. Patients undergoing orthognathic surgery are reported to have a high rate of PONV, especially those undergoing bimaxillary surgery. Activation of cholinergic system plays an important role in the development of PONV. Penehyclidine is an muscarinic antagonists which selectively block …

anesthesia
body mass index
vomit
postoperative nausea
analgesia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Stress Management and Biological Age in Breast Cancer Patients.RCT  

Intense stress has harmful effects on the body, contributing to various disorders. Breast cancer patients experience a build-up of stress due to their diagnosis and treatments. Stress can cause epigenetic changes in a cellular level (such as accelerated increase in biological age) that may negatively affect oncological treatments. This study …

  • 0 views
  • 08 Sep, 2023
  • 1 location
RCT on Effect of Lymph Node Mapping by Indocyanine Green Via Submucosal or Subserosal Injection

The purpose of this study was to evaluate whether submucosal or subserous injection of indocyanine green during laparoscopic lymph node dissection of gastric cancer was different in tracing lymph nodes of gastric cancer. The patients with gastric adenocarcinoma (cT1-4a, Nmuramel +, M0) were studied.

gastric cancer
gastric adenocarcinoma
signet ring cell carcinoma
cancer
carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Multiomics After Cold Pressor Test of People Who Are Unable to Have Headache

Headaches are extremely common illnesses with a combined lifetime prevalence of 90-99% in Europe. Despite this high prevalence, there are persons who have never, in their whole life, encountered a headache. The aim of the study is to identify factors that protect against headache by studying multiomics in people who …

headache
5 minutes
pressor
after pain
cold
  • 0 views
  • 16 Feb, 2024
  • 1 location
Longitudinal Immune-phenotyping of HCC Following MK-3475

The study comprises a main study of pembro-treated HCC patients and a sub-study of untreated HCC patients. In the main study, patients will be treated with pembrolizumab as neoadjuvant treatment approximately 4 weeks prior scheduled surgery. Adjuvant treatment with pembrolizumab with commence at approximately 4 weeks post-surgery for up to …

international normalized ratio
immunomodulator
radiofrequency ablation
oncolytic virus therapy
serum pregnancy test
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery

Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience of surgeons. The identification of nerves is often needed in gynecological surgery, such as the obturator nerves in …

sarcoma
uterine myomatosis
endometriosis
pelvic lymphadenectomy
cervical cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

x-rays
sarcoma
renal cell carcinoma
karnofsky performance status
relieve pain
  • 0 views
  • 16 Feb, 2024
  • 1 location
Headache Provocation of People Who Are Unable to Have Headache

Headaches are extremely common illnesses with a combined lifetime prevalence of 90-99% in Europe. Despite this high prevalence, there are persons who have never, in their whole life, encountered a headache. The aim of the study is to identify factors that protect against headache by studying headache after provocation in …

headache
isosorbide mononitrate
  • 0 views
  • 16 Feb, 2024
  • 1 location