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Found 1695 clinical trials
TAS-102 and Oxaliplatin for the Treatment of Refractory Stage IV Colon Cancer

This phase II trial studies how well TAS-102 and oxaliplatin work in treating patients with stage IV colon cancer. Drugs used in chemotherapy, such as TAS-102 and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or …

tas-102
adjuvant chemotherapy
recurrent colorectal cancer
measurable disease
colorectal cancer
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulating tumor DNA in the blood. This research study involves the following investigational drugs: Ipatasertib Atezolizumab

mastectomy
white blood cell count
granulocyte colony stimulating factor
serum bilirubin
cfdna
  • 0 views
  • 16 Feb, 2024
  • 1 location
Virtual Reality for Postoperative Pain Management

This trial studies an active virtual reality (VR) experience as a means for non-pharmacologic postoperative pain management among patients after head and neck surgery. Investigators will assess differences in pain scores, analgesic use, and subjective patient experiences between patients participating in a VR activity and patients participating in the same …

analgesic
analgesia
postoperative pain
analgesics
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Effectiveness of Telerehabilitation-Based Physiotherapy in COVID 19 Patients

Problems such as breathlessness, exercise intolerance and loss of peripheral muscle strength can be observed in individuals who have been diagnosed with COVID19 and have been discharged.

dyspnea
therapy intervention
breathlessness
  • 0 views
  • 05 Aug, 2020
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy

During dose escalation, participants will take various doses of venetoclax as a tablet by mouth once a day and capecitabine as a tablet by mouth twice per day on days 1 - 14 of each cycle for approximately 30 weeks.

primary tumor
stage iv breast cancer
measurable disease
capecitabine
blood test
  • 0 views
  • 16 Feb, 2024
  • 16 locations
Resting Full-cycle Flow Ratio (RFR) Versus Angiography to Guide Revascularization Strategy in Patients Undergoing Coronary Artery By-pass Grafting (CABG)

Differently from FFR which is a measurement performed in maximal hyperemia, the RFR is a measurement that is performed in rest and therefore may predict better than FFR the baseline equilibriums that could lead to graft failure, while it has similar capacity to identify hemodynamically significant stenosis as FFR. It …

angiography
coronary artery stenosis
stenosis
percutaneous coronary intervention
hyperemia
  • 0 views
  • 05 Aug, 2020
Ginko Biloba Versus Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis

While one of theory of nocturnal enuresis is deep sleep in children , this the main cornerstone in using Alarm as line of management .On the other hand drugs used in rehabitation of sleep rhythm seems to be with great benefits in management as GINKO BILOBA Ginkgo biloba leave extract …

Accepts healthy volunteers
  • 0 views
  • 07 Apr, 2025
A Feasibility Study on Ultrafiltration and Blood Volume Measurements

The objective of this feasibility study is to characterize the performance of CHF Solutions' ultrafiltration system, the Aquadex FlexFlow System with the hematocrit (HCT) feature in conjunction with Daxor's blood volume analyzer (BVA-100). Monitor blood volume changes during UF therapy as a potential mean to guide the removal of fluid …

pitting edema
heart failure
hypervolemia
edema
fluid overload
  • 0 views
  • 16 Feb, 2024
  • 1 location
Tolerability Safety and Efficacy of Sigh Breaths During NIMV in Motor Neuron Disease

Non-invasive mechanical ventilation (NIMV) is the recommended standard of care as initial therapy for patients with motor neuron disease (MND) with deterioration of the respiratory function. SIGH_01 study is aimed at investigating the tolerability, safety profile and efficacy of sigh breaths during non-invasive mechanical ventilation in patients with MND in …

non-invasive ventilation
noninvasive ventilation
motor neuron disease
mechanical ventilation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Taiwan "Aerosol Box" Versus UMMC "Intubation Box"

Anaesthetists with more than 5 years of clinical experience in intubating airways as well as more than 20 successful intubations using videolaryngoscopy , will be available to participate. This study will employ manikin and will be a randomized cross-over trial, conducted in UM.

intubation
covid-19
  • 0 views
  • 05 Aug, 2020