Found 91 clinical trials
Predicted Biomarkers of CDK4/6 Inhibitors (Palbociclib) in ER-positive Metastasis Breast Cancer
This is a multi-center, observational study designed to explore the regulatory mechanism of palbociclib correlative pathways in therapeutic process of breast cancer, employing next generation sequencing (NGS) on DNA and RNA. This study also monitor the clonal evolution of genes by tracing the ctDNA.
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- 16 Feb, 2024
- 1 location
A Prospective Multi-centre Single-blinded Study of UroCAD for Urothelial Carcinoma Diagnosis and Follow-up
Urothelial carcinoma (UC) is common malignancy and is considered to be one of the most expensive cancers. The traditional diagnostic methods of UC present with some shortcomings. For example, the specificity of CTU remains low while cystoscopy is invasive and expensive. Therefore, a noninvasive diagnostic method with high accuracy is …
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- 16 Feb, 2024
- 1 location
Minimal Invasive Axillary Staging and Treatment After Neoadjuvant Systemic Therapy in Node Positive Breast Cancer
Today, the majority of clinically node positive (cN+) breast cancer patients is treated with neoadjuvant systemic therapy (NST). Axillary staging and treatment after NST in cN+ patients are areas of controversy. Patients with a pathological complete response (pCR) of the axillary lymph nodes are not expected to benefit from axillary …
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- 05 Aug, 2020
Staging Endometrial caNcer Based on molEcular ClAssification
The SENECA study tries to evaluate the rate of lymph node involvement depending on the molecular subgroup in early-stage endometrial cancer (I/II) patients undergoing surgery as part of their treatment.
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- 01 Feb, 2023
- 1 location
Efficacy of Chemopreventive Agents on Disease-free and Overall Survival in Patients With Pancreatic Ductal Adenocarcinoma: The CAOS Study
400 patients with the following inclusion criteria will be enrolled in 3 years: cytological or histological diagnosis of pancreatic ductal adenocarcinoma in any portion of the gland, with or without metastases in other sites patient age between 18 and 90 years any medicine or drug in the daily patient therapy …
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- 16 Feb, 2024
- 1 location
Oxaliplatin Adjuvant Chemotherapy After Curative Resection of Primary Colon Cancer
According to general medical guidelines, adjuvant chemotherapy is used after curative resection of high-risk stage II or III primary colon cancer. However, there exist limitations using clinical trial data acquired from highly selected subjects in a controlled environment. For example, patients aged over 70 years old were in many cases …
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- 16 Feb, 2024
- 1 location
Optimal EGFR TKIs Treatment Strategies for Lung Adenocarcinoma Harboring EGFR Exon 19 Deletion Variants
To determine the optimal EGFR TKIs treatment strategies for lung adenocarcinoma harboring EGFR exon 19 deletion variants
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- 05 Aug, 2020
Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic
The primary purpose of this study is to gain an understanding of how experiences during the COVID-19 pandemic, regardless of COVID-19 status, may have impacted multiple domains of health-related quality of life and other areas such as COVID-19 specific psychological distress, and disruptions to health care, finances and social interactions. …
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- 05 Aug, 2020
The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies
These patients will receive a targeted dye to aid in the resection of these metastases. We plan to assess ICG as it relates to: Diagnostic accuracy using pathologic correlation as gold standard measure Short and long term event free and overall survival
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- 05 Aug, 2020
PET-CT Predicting Segement Specific Lymph Nodes Metastasis
The final pathological results were used to assess the predictive value of PET-CT for segment-specific lymph node metastasis.
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- 02 Aug, 2023
- 1 location