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Found 810 clinical trials
Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy

This is a Phase III, multicenter, randomized, open-label study designed to evaluate the efficacy, safety, and pharmacokinetics of atezolizumab given in combination with cabozantinib compared with docetaxel monotherapy in patients with metastatic NSCLC, with no sensitizing EGFR mutation or ALK translocation, who have progressed following treatment with platinum-containing chemotherapy and …

carcinoma
hiv test
hepatitis b surface antigen
cancer
stage iv non-small cell lung cancer
  • 0 views
  • 16 Feb, 2024
  • 98 locations
High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

This is an international multicenter, open-label, randomized phase III trial including three sequential randomizations to assess efficacy of induction and consolidation chemotherapies and radiotherapy for patients with high-risk neuroblastoma.

bone disease
oximetry
hearing impairment
hypericum perforatum
phenytoin
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Trial of SHR-1802 in Patients With Failure of Standard Treatment for Advanced Malignant Tumours

The primary purpose of this study is to see if SHR-1802 is safe and tolerable for patients with locally advanced/unresectable or metastatic malignancies that are refractory to available therapy or for which no standard therapy is available.

bone marrow procedure
measurable disease
cancer
  • 0 views
  • 05 Aug, 2020
Clinical Study of DC-CIK Cells as a Post-remission Treatment for Malignant Tumors

Screening stage Evaluation of disease Grouping of patients Infusion of cells Surveillance of adverse effect

solid tumour
immunosuppressive agents
cancer therapy
malignant solid neoplasm
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
CyPep-1 Injections in Cancer Inducing Lymphocyte Infiltrate Accumulations

This Phase I/IIa trial is designed to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of CyPep-1 when administered directly into malignant tumors. Additionally, the trial will monitor anti-tumor effects on both injected lesions and distant non-injected deposits.

  • 0 views
  • 16 Feb, 2024
  • 2 locations
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.

Accepts healthy volunteers
  • 0 views
  • 25 Jul, 2023
  • 22 locations
Exercise and Tumor Blood Flow in Breast Cancer Patients

This research aims at investigating tumor blood flow response to acute exercise in human cancer patients. It is hypothesized and expected that acute exercise increases tumor blood flow, which could plausibly increase the efficacy of cancer treatment.

cancer treatment
  • 0 views
  • 05 Aug, 2020
Study of Adavosertib(AZD1775) in Japanese Patients With Advanced Solid Tumours

This is a phase I, open-label study to assess the safety, tolerability, pharmacokinetics(PK) and anti-tumour activity of adavosertib in Japanese patients with advanced solid tumours. This study consists of 2 cohorts, Cohort1 and Cohort2.

  • 0 views
  • 05 Aug, 2020
Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator

The purpose of the study is to determine if family caregivers of neuro-oncology patients feel less burdened by utilizing the Electronic Social Network Assessment Program (eSNAP) + the Caregiver Navigator.

ATM
brain tumor
malignant brain tumor
primary brain tumors
  • 0 views
  • 16 Feb, 2024
  • 1 location
SBRT for Breast Cancer Oligometastases

Response and progression for these metastases will be evaluated using the revised Response Evaluation Criteria in Solid Tumors (RECIST) guideline (version 1.1). Changes in the largest diameter (unidimensional measurement) of the tumor lesions is used in the RECIST criteria.

breast neoplasm malignant female
metastasis
bone scan
positron emission tomography
bone metastases
  • 0 views
  • 05 Aug, 2020