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Found 1426 clinical trials
What Works and Why? Eye Movement Desensitization and Reprocessing as a Potential Treatment for Substance Use Disorders  

EMDR is one of the most effective interventions for Post-Traumatic Stress Disorder (PTSD), and has been applied to other disorders that are often comorbid with trauma, such as psychosis and depression, with promising results. Nevertheless, its application in SUD is still limited. Taken altogether, there is a need to clarify …

  • 0 views
  • 08 Aug, 2022
  • 1 location
EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Catheter Placement

This phase II trial investigates the effect of EXPAREL compared to lidocane as a local anesthetic in patients who are undergoing pleuroscopy with pleural biopsy and indwelling pleural catheter placement. This trial aims to see whether EXPAREL or lidocane is able to make patients more comfortable.

  • 0 views
  • 15 Sep, 2021
  • 1 location
Fulvestrant Versus Capecitabine as Maintenance Therapy After First-line Combination Chemotherapy in Patients With HR+/HER2- Metastatic Breast Cancer

This phase III trial aims to compare the progression free survival (PFS) and safety of fulvestrant or capecitabine as maintenance therapy after first-line combined chemotherapy in hormone receptor-positive, human epidermal growth factor receptor-2 negative metastatic breast cancer.

metastasis
growth factor
cish
chemotherapy regimen
epidermal growth factor
  • 0 views
  • 16 Feb, 2024
  • 7 locations
Markers to Evaluate the Efficacy of PH-based Regimen as a Neoadjuvant Therapy for Operable HER2 Positive Breast Cancer

This study is to explore the markers in early prediction of the efficacy of pre-operative pertuzumab plus trastuzumab (PH) combined with chemotherapy for early stage or locally advanced human epidermal growth factor receptor-2 (HER-2) positive primary breast cancer.

growth factor
her2+ breast cancer
HER2
epidermal growth factor
pertuzumab + trastuzumab
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)

This Phase III study will be conducted to evaluate the efficacy and safety of YH25448 as first-line treatment in locally advanced or metastatic Non-small Cell Lung Cancer (NSCLC) patients with EGFR mutations

gefitinib
measurable disease
small cell lung cancer
curative surgery
EGFR
  • 0 views
  • 16 Feb, 2024
  • 29 locations
Vacuum Assisted Biopsy Immediately Before Surgery as an Intra- or Pre-Operative Surrogate for Patient Response to Neoadjuvant Chemotherapy for Breast Cancer

Neoadjuvant chemotherapy (NAC) is common practice in the primary treatment of breast cancer, leading to a complete pathologic remission (pCR) of the tumor in more than 50% in aggressive tumor types. As NAC induces different response patterns, radiologic imaging is not sufficiently accurate in predicting residual disease. Because of this …

HER2
adjuvant chemotherapy
invasive breast cancer
remission
immunomodulators
  • 0 views
  • 16 Feb, 2024
  • 16 locations
Django Test Trial 01  

Productivity PackThe Productivity Pack is a bundle of Premium plugins designed to enhance document editing and accelerate content creation for you and your team, available for no extra cost with a CKEditor base subscription.Productivity Pack Minutes Saved by the UserFictional DataProductivity Pack FeaturesMinutes SavedDocument Outline1237Table of Contents1237Format Painter1162Templates1225Slash Commands1247Paste from …

  • 0 views
  • 12 Dec, 2024
  • 1 location
Low-dose AZA Combined With Short Term CAG Derived Regimen as a Bridging Treatment in Patients With Advanced MDS Prior to Allo-HSCT

This single arm, prospective study on the feasibility of a bridging treatment with low-dose azacitidine (AZA) in combination with short term CAG derived regimen prior to allogeneic stem cell transplantation (allo-HSCT) in patients with advanced myelodysplastic syndromes (MDS) .

myelodysplastic syndrome
raeb
stem cell transplantation
cag protocol
myelodysplastic syndromes
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder

The purpose of the study is to evaluate the effect of seltorexant, compared to placebo, as an add-on medication to an antidepressant, on next-day driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) from an on-road driving test.

citalopram
anxiety
fluoxetine
vortioxetine
desvenlafaxine
  • 0 views
  • 16 Feb, 2024
  • 2 locations
A Study to Evaluate the Efficacy Safety and Tolerability of IMU-838 as Addition to Investigator's Choice of Standard of Care Therapy in Patients With Coronavirus Disease 19 (COVID-19)

To date approximately 600 individuals have received IMU-838 (or a drug similar to IMU-838 that contains the same active substance as IMU-838) in research studies.

cough
SARS
coronavirus infection
periodic abstinence
covid-19
  • 0 views
  • 05 Aug, 2020