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Found 787 clinical trials
First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Primary Objective: To determine the maximum tolerated dose (MTD) of SAR442257 administered as a single agent in patients with relapsed and refractory multiple myeloma (RRMM) and refractory non-Hodgkin lymphoma (RR-NHL), and determine the recommended Phase 2 dose (RP2D) Secondary Objectives: To characterize the safety profile of SAR442257 To characterize the …

multiple myeloma
cancer therapy
ejection fraction
diffuse large b-cell lymphoma
hair thinning
  • 0 views
  • 04 Dec, 2020
  • 5 locations
19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers

The purpose of this study is to test the safety of 19(T2)28z1xx CAR T cells in people with relapsed/refractory B-cell cancers. The researchers will try to find the highest dose of 19(T2)28z1xx CAR T cells that causes few or mild side effects in participants. Once they find this dose, they …

venetoclax
conjugated bilirubin
lenalidomide
oxygen saturation
diffuse large b-cell lymphoma
  • 0 views
  • 05 Aug, 2020
VR-CAP in the First-line Treatment for Patients With Marginal Zone Lymphoma

This is a prospective single arm, multi-center, phase II clinical trial to observe the efficacy and safety of VR-CAP (Velcade and Rituximab-Cyclophosphamide, Epirubicin and Prednisone) in the first-line treatment for patients with marginal zone lymphoma.

lymphoma
marginal zone lymphoma
cyclophosphamide
prednisone
rituximab
  • 0 views
  • 05 Aug, 2020
A Study of CT-RD06 Cell Injection in Patients With Relapsed or Refractory CD19+ B-cell Hematological Malignancy

A study of CT-RD06 cell injection in patients with relapsed or refractory CD19+ B-cell hematological malignancy.

ejection fraction
oxygen saturation
b-cell acute lymphoblastic leukemia
diffuse large b-cell lymphoma
chemotherapy regimen
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of CTA101 UCAR-T Cell Injection in Patients With Relapsed or Refractory CD19+ B-line Hematological Malignancy

A study of CTA101 UCAR-T cell injection in patients with relapsed or refractory CD19+ B-line hematological malignancy

ejection fraction
oxygen saturation
b-cell acute lymphoblastic leukemia
cell transplantation
diffuse large b-cell lymphoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Targeted Drug Combined With CHOP in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma

This prospectivemulti-centeropen-label, controlled study will evaluate the efficacy and safety of targeted drug in combination with CHOP in treatment of newly diagnosed peripheral T-cell lymphoma.

t-cell lymphoma
lymphoma
measurable disease
peripheral t-cell lymphoma
pet/ct scan
  • 0 views
  • 05 Aug, 2020
Azacitidine Combined With Chidamide in the Treatment of Newly Diagnosed PTCL Unfit for Conventional Chemotherapy

This prospective, open-label, single-arm study will evaluate the efficacy and safety of azacitidine in combination with chidamide in treatment of newly diagnosed peripheral T-cell lymphoma unfit for conventional chemotherapy.

t-cell lymphoma
lymphoma
tucidinostat
azacitidine
peripheral t-cell lymphoma
  • 0 views
  • 16 Feb, 2024
  • 1 location