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Found 787 clinical trials
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Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging

However, the incidence of human papillomavirus (HPV) related oropharyngeal carcinomas is increasing. It is known that HPV+ and HPV- tumors have a different reaction to (chemo)radiotherapy. The exact mechanisms underlying these differences is not yet known but might be caused by changes in vascularity.

ct perfusion
carcinoma
squamous cell carcinoma of the head and neck
chemoradiotherapy
squamous cell carcinoma
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  • 16 Feb, 2024
  • 1 location
Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers

This will include patients with either Human papilomavirus-associated (HPV-associated) oropharyngeal cancer (OPC), Human papilomavirus-negative (HPV-negative) OPC or Base of Skull HNC. Single centre prospective interventional phase I/II study (main study) made up of 3 independent arms (on the condition of success of the feasibility stage).

metastasis
head and neck cancer
chemo-radiotherapy
head and neck carcinoma
carcinoma
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  • 16 Feb, 2024
  • 1 location
COVID-19 Convalescent Plasma for Mechanically Ventilated Population

The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it can improve patients' health when they are sick with COVID-19.

x-rays
mechanical ventilation
chest x-ray
acute respiratory syndrome (sars)
pneumonia
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  • 16 Feb, 2024
  • 1 location
COVID-19 Convalescent Plasma for the Treatment of Hospitalized Patients With Pneumonia Caused by SARS-CoV-2.

The purpose of this study is to see if this plasma can be safely used in humans with COVID-19 and to see if it improves patients' health as compared to not using it in patients with pneumonia caused by SARS-CoV-2.

x-rays
chest x-ray
pneumonia
ct scan
covid-19
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  • 05 Aug, 2020
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy.

metastasis
neck dissection
robotic surgery
chemo-radiotherapy
carcinoma
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  • 16 Feb, 2024
  • 1 location