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Found 1695 clinical trials
Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma

The objective of this study is to evaluate, in patients diagnosed with prostate cancer who undergo radical prostatectomy and who require postoperative radiotherapy, tolerance in terms of acute and chronic GU and GI toxicity and efficacy in terms of biochemical control and survival, as well as of quality of life, …

bone scan
adenocarcinoma
adjuvant
immunological adjuvant
prostatectomy
  • 0 views
  • 16 Feb, 2024
  • 19 locations
Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot

Remote ischemic conditioning (RIC) consists of intermittent application of a device such as a blood pressure cuff to a limb to induce non-lethal ischemia. Studies in animals with cardiac arrest as well as in humans with acute myocardial infarction suggest that RIC before or after restoration of blood flow may …

ischemia
reperfusion injury
cardiac arrest
resuscitation
out-of-hospital cardiac arrests
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effects of Age and Obesity on Brain Insulin Sensitivity

Additionally, structural changes and cognitive processes will be assessed as secondary variables.

insulin sensitivity
glucose tolerance test
oral glucose tolerance test
chronic disease
hemoglobin a1c
  • 0 views
  • 05 Aug, 2020
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

This clinical trial is studying two immunotherapy drugs (nivolumab and ipilimumab) given together as a possible treatment for INI1-negative tumors.

lipase
epithelioid sarcoma
kidney function tests
rhabdoid tumor
measurable disease
  • 0 views
  • 05 Aug, 2020
Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment

The modified masks will be made from masks that are already available as well as filters available in the pulmonary department at the Oklahoma City VA Health Care System

covid-19
coronavirus infection
  • 0 views
  • 16 Feb, 2024
  • 1 location
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

total cavopulmonary connection
  • 0 views
  • 05 Aug, 2020
CPX-351 in Higher Risk Myelodysplastic Syndromes

Study of the efficacy of CPX-351 treatment in patients with higher risk myelodysplastic syndromes : as first line treatment or after hypomethylating agents failure

conjugated bilirubin
cardiovascular disease
chronic myelomonocytic leukemia
central nervous system leukemia
leukemia
  • 0 views
  • 16 Feb, 2024
  • 12 locations
Low Dose Ruxolitinib in Combination With Methylprednisolone

This study is to determine the efficacy and safety of combined Low dose Ruxolitinib With Methylprednisone as Initial Therapy for the aGVHD(acute graft-versus-host disease )

tumorigenicity
methylprednisolone
graft versus host disease
allogeneic hematopoietic stem cell transplant
acute graft versus host disease
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.

Patients who continue to be benefit after 6 cycles' treatment will receive additional cycles of treatment until progression of disease, unacceptable toxicity is observed or administrative discontinuation. (As long as it is proven safe).

bone marrow procedure
hydroxyurea
white blood cell count
azacitidine
leukemia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Vestibular Nerve Stimulation to Improve Sleep

A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings The purpose of this investigation device study is to collect data that will …

insomnia
  • 0 views
  • 16 Feb, 2024
  • 1 location