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Found 792 clinical trials
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

This phase II study investigates how well radium-223 works in treating patients with castration-resistant prostate cancer than has spread to the bones (bone metastases). Prostate cancer is the most common cancer in men and the second leading cause of cancer death.

prostate-specific antigen
stage iv prostate cancer
metastatic hormone refractory prostate cancer
carcinoma
metastatic malignant neoplasm
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cancer Therapy Effects on the Heart

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death.

pediatric cancer
cancer treatment
cancer
pediatric
anthracyclines
  • 0 views
  • 16 Feb, 2024
  • 1 location
Epigenetic Changes in Head and Neck Cancer

With this study, the investigators will investigate the epigenetic changes, which may contribute to the development of head and neck squamous cell carcinomas.

carcinoma
neck cancer
head and neck cancer
squamous cell carcinoma
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Microbiome of Pancreatic Cancer: "PANDEMIC" Study

These variations could affect the surgical outcome and increase the risk of life-threatening infections supported by multidrug-resistant bacteria. The identification of microbial signatures with tumor specificity may have a potential role in postoperative risk stratification. Variation of pancreatic, intestinal or bile microbiome and their relationship can be investigated and measured …

breast ductal carcinoma
adenocarcinoma
pdac
pancreatic ductal adenocarcinoma
pancreatic cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Childhood Cancer Survivors' Affective Response to Exercise

The primary objective of this study is to assess the feasibility of administering the Personalized Single-Category Implicit Association Test (PSC-IAT) to young adult survivors of childhood cancer. Participants will perform a total of three trials of a cognitive task before and after their scheduled SJLIFE cardiovascular stress testing.

  • 0 views
  • 13 Mar, 2023
  • 1 location
Standalone OMNI Surgical System for Open-angle Glaucoma

The emergence of minimally invasive glaucoma surgeries (MIGS) has seen a variety of potential innovative surgical alternatives to help better control intraocular pressure (IOP). The OMNI Surgical System (Sight Sciences, Menlo Park, CA, USA) is a promising MIGS procedure. It combines two procedures known as trabeculotomy and viscodilation of Schlemm's …

laser trabeculoplasty
intraocular pressure
trabeculotomy
glaucoma
glaucoma surgery
  • 0 views
  • 16 Feb, 2024
  • 1 location
CT-based Radiomic Algorithm for Assisting Surgery Decision and Predicting Immunotherapy Response of NSCLC

Besides, response and long term clinical benefit of immunotherapy of advanced NSCLC lung cancer patients could also be predicted by this strategy.

chest ct
adenocarcinoma
non-small cell lung cancer
lung cancer
lung adenocarcinoma
  • 0 views
  • 05 Aug, 2020
Post-Marketing Follow-Up of Long-term Type Ureteral Stent Set

Although there are several reports regarding the effectiveness of long-term ureteral stents for malignancy ureteral obstruction, ureteral stricture and urolithiasis, the experience is limited about the long-term ureteral stents made by Taiwan.

  • 0 views
  • 16 Feb, 2024
  • 1 location
PET-CT Predicting Segement Specific Lymph Nodes Metastasis

This study is a multicenter prospective clinical study that aims to evaluate the predictive value of preoperative PET-CT results (such as SUV uptake, size of tumor lymph nodes, and differences in FDG uptake compared to surrounding tissues) for lymph node metastasis in patients with non-small cell lung cancer.

  • 0 views
  • 02 Aug, 2023
  • 1 location
Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

carcinoma of the cervix
carcinoma
chemoradiotherapy
stage iii non-small cell lung cancer
small cell lung cancer
  • 0 views
  • 05 Aug, 2020