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Found 1835 clinical trials
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad

In addition, semi-structured interviews will be conducted to examine the acceptability and satisfaction with the intervention.

psychotropic drugs
hearing impairment
behavior modification
actigraphy
sleep disorder
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Host-pathogen Interactions During SARS-CoV-2 Infection

In particular, children forms and pauci-symptomatic disease in adults may be linked to a more robust innate immune response, including better production of IFN-I.

hypercytokinemia
fever
cytokine storm
respiratory infection
respiratory symptom
  • 0 views
  • 16 Feb, 2024
  • 12 locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.

lymphoma
lung cancer
non-small cell lung cancer
solid tumor
pembrolizumab
  • 0 views
  • 16 Feb, 2024
  • 39 locations
The Effect and Safety of Low-level Laser Therapy in Acute Decompensated Heart Failure Patients.

The therapeutic dose is easy to operate, and the instrument output frequency, power and time can be controlled. Through the clinical physiological function test plus the verification and analysis of the quantitative test values, it will be more able to define the new role of laser acupuncture treatment in patients …

cardiogenic pulmonary edema
fainting
syncope
heart failure
ischemic cardiomyopathy
  • 0 views
  • 05 Aug, 2020
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms

The study is a prospective, randomized, controlled investigation designed for comparison of two groups for the reduction of respiratory distress in a CoViD-19 population, using gammaCore Sapphire (nVNS) plus standard of care (active) vs. standard of care alone (SoC), the control group. The gammaCore (nVNS) treatments will be used acutely …

respiratory symptoms
respiratory distress
vagus nerve stimulation
vagal nerve stimulation
respiratory symptom
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Daily-Activity-Focused, Strategy-Based Educational Programme for Informal Dementia Carers

Caregiving burden will be assessed after receiving the programme. Statistical analysis of caregiving burden will follow the intention-to-treat principle, employing paired t-tests and linear modelling.

  • 0 views
  • 16 Jun, 2025
Decitabine Treatment in HPV-Induced Anogenital and Head and Neck Cancer Patients After Radiotherapy or as Novel Late Salvage

The duration of the trial for each patient is expected to be 6 months (two 28 day cycles of study treatment plus four months of additional follow-up). The overall duration of the trial is expected to be approximately 42 months.

bilateral oophorectomy
progressive disease
extranodal extension
cancer
hpv dna
  • 0 views
  • 16 Feb, 2024
  • 1 location
Bioequivalence and the Tolerability and Antitumor Activity of Selinexor Combination Treatment

During the Monotherapy Period, the bioequivalence/relative bioavailability of different formulations of selinexor will be evaluated using a 2-sequence crossover design. During the Combination Therapy Period, the safety and preliminary anti-tumor activity of selinexor in combination with docetaxel (for patients with NSCLC) or pembrolizumab (for patients with CRC) will be evaluated.

selinexor
lung cancer
non-small cell lung cancer
docetaxel
drug test
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Motor Learning in Knee Osteoarthritis

In physiotherapy, motor learning can be optimized by using instructions and feedback, targeting an external focus of attention, when learning specific movement patterns.

gait evaluation
exercise therapy
range of motion
osteoarthritis
non-surgical treatment
  • 0 views
  • 05 Aug, 2020
Physiological Changes Induced Through MEP Conditioning in People With SCI

Because these connections are important in movement control, when they are not working well, movements may be disturbed. Researchers have found that people can learn to strengthen these connections through training. Strengthening these connections may be able to improve movement control and recovery after injuries.

spinal cord disorder
thoracic injuries
weakness
neurologic findings
spasticity
  • 0 views
  • 16 Feb, 2024
  • 1 location