Found 734 clinical trials
Myocardial Contrast Echocardiography in Septic Patients
Myocardial microcirculatory alterations may be involved in the pathogenesis of acute cardiac dysfunction or septic cardiomyopathy in septic patients. The investigators study the cardiac function (systolic and diastolic) with two-dimensional echocardiography (TTE), and the myocardial microcirculation with contrast echocardiography (MCE) and sulphur hexafluoride microbubbles Sonovue injection in ICU septic patients.
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- 16 Feb, 2024
- 1 location
VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients
This study is being conducted to evaluate the safety and effectiveness of VBI-S in elevating the blood pressure of septic shock patients with absolute or relative hypovolemia.
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- 16 Feb, 2024
- 2 locations
Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients
In the intensive care unit (ICU), acute RVF is mainly due to the acute respiratory distress syndrome (ARDS), sepsis or septic shock, and less often to severe pulmonary embolism or RV infarction. The anatomical complexity of the RV precludes any geometrical assumption to estimate its volume, hence its ejection fraction …
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- 16 Feb, 2024
- 2 locations
Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia
2019 new coronavirus (2019-nCoV) infected pneumonia, namely severe acute respiratory infection (SARI) has caused global concern and emergency. There is a lack of effective targeted antiviral drugs, and symptomatic supportive treatment is still the current main treatment for SARI. Vitamin C is significant to human body and plays a role …
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- 16 Feb, 2024
- 1 location
Anti-inflammatory Clarithromycin for Improving COVID-19 Infection Early
Recent information appearing from different countries suggest that treatment of Coronavirus disease 2019 (COVID-19) with hydroxychloroquine or with a combination of hydroxychloroquine and azithromycin has either an indifferent effect on viral replication or substantial cardiotoxicity. This is a clinical trial aiming to prove that addition of oral clarithromycin to treatment …
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- 16 Feb, 2024
- 9 locations
A Study of COVID 19 Convalescent Plasma in High Risk Patients With COVID 19 Infection
Purpose of Study The purpose of this study to evaluate, the effectiveness of convalescent plasma in combatting the symptoms and effects of the coronavirus disease, COVID-19. Beyond supportive care, there are no proven treatment options for COVID-19.
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- 05 Aug, 2020
Epidemiologic Clinical Molecular Characteristics of Hospital Employees With or Without Covid-19 Infection
The study cohort will be enrolled among all Humanitas group employees (including ICH, Humanitas University and Gavazzeni), and two validation cohorts. Participants will be asked consent for the research use of blood, pharyngeal swab, and for those hospitalized for COVID-19, also for the bronchoalveolar lavage and fecal samples. Biological samples …
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- 16 Feb, 2024
- 1 location
COVID-19: Study of INFLAmmasome and PLAtelets Functions
COVID-19 pandemic is a severe viral sepsis characterized by the occurrence of Acute respiratory distress syndrome (ARDS) whose pathophysiology is little described
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- 05 Aug, 2020
Clinical Application of Quantitative Ultrasonographic Analysis in Early Kidney Injury
The purpose of this study was to quantify overall blood flow and renal cortical perfusion in patients with septic acute kidney injury (AKI) using ultrasound (US) Doppler and contrast-enhanced ultrasound (CEUS).
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- 11 Jan, 2023
- 1 location
Tissue Models for Liver Disease (TIMOLD)
The human immune response to bacterial and viral local and systemic infection are fairly well understood, but we lack details on the earliest phases. Better knowledge of these events would be important for the prevention and treatment of severe bacterial or viral disease.
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- 24 May, 2022
- 1 location