Found 1816 clinical trials
SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer
TASOX can be safely and efficaciously delivered after short course radiation, resulting in significant pathologic downstaging, allowing for an R0 pelvic resection, and providing local control in appropriately selected stage II/III rectal cancer patients treated with contemporary TME-based surgery.
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- 05 Aug, 2020
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression
The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
- 0 views
- 16 Feb, 2024
- 39 locations
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad
In addition, semi-structured interviews will be conducted to examine the acceptability and satisfaction with the intervention.
- 0 views
- 16 Feb, 2024
- 2 locations
Host-pathogen Interactions During SARS-CoV-2 Infection
In particular, children forms and pauci-symptomatic disease in adults may be linked to a more robust innate immune response, including better production of IFN-I.
- 0 views
- 16 Feb, 2024
- 12 locations
Decitabine Treatment in HPV-Induced Anogenital and Head and Neck Cancer Patients After Radiotherapy or as Novel Late Salvage
The duration of the trial for each patient is expected to be 6 months (two 28 day cycles of study treatment plus four months of additional follow-up). The overall duration of the trial is expected to be approximately 42 months.
- 0 views
- 16 Feb, 2024
- 1 location
Bioequivalence and the Tolerability and Antitumor Activity of Selinexor Combination Treatment
During the Monotherapy Period, the bioequivalence/relative bioavailability of different formulations of selinexor will be evaluated using a 2-sequence crossover design. During the Combination Therapy Period, the safety and preliminary anti-tumor activity of selinexor in combination with docetaxel (for patients with NSCLC) or pembrolizumab (for patients with CRC) will be evaluated.
- 0 views
- 16 Feb, 2024
- 3 locations
The Effect and Safety of Low-level Laser Therapy in Acute Decompensated Heart Failure Patients.
The therapeutic dose is easy to operate, and the instrument output frequency, power and time can be controlled. Through the clinical physiological function test plus the verification and analysis of the quantitative test values, it will be more able to define the new role of laser acupuncture treatment in patients …
- 0 views
- 05 Aug, 2020
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms
The study is a prospective, randomized, controlled investigation designed for comparison of two groups for the reduction of respiratory distress in a CoViD-19 population, using gammaCore Sapphire (nVNS) plus standard of care (active) vs. standard of care alone (SoC), the control group. The gammaCore (nVNS) treatments will be used acutely …
- 0 views
- 16 Feb, 2024
- 1 location
Comparison of Epidural Combined and Dural Puncture Labor Epidural on Pain and Course of Vaginal Delivery
The three standard techniques used for labor analgesia, thus epidural, combined spinal-epidural and dural puncture epidural will be compared regarding their impact on pain intensity, analgesic and local anesthetic consumption and course of vaginal delivery in a prospective, randomised, double blind manner
- 0 views
- 16 Feb, 2024
- 2 locations
Bintrafusp Alfa in Previously Treated Patients With Recurrent and Metastatic (R/M) Non-keratinizing Nasopharyngeal Carcinoma (NPC)
This would be a phase II prospective single arm mono-institutional study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of bintrafusp alfa in previously treated patients with recurrent and metastatic (R/M) non-keratinizing nasopharyngeal carcinoma (NPC).
- 0 views
- 16 Feb, 2024
- 1 location