Found 1816 clinical trials
A Rhinovirus Challenge Study to Investigate Exacerbations and Immune Responses in Bronchiectasis (BARRIER)
Participants will be asked to keep a daily record of their symptoms throughout the study.
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- 23 Apr, 2025
- 1 location
An Open-Label Study to Investigate the Safety of Single Ascending Doses in Children and Adolescents With Dravet Syndrome
Stoke Therapeutics is evaluating the safety and tolerability of single ascending doses of STK-001 in patients with Dravet syndrome. Change in seizure frequency and quality of life will be measured as secondary endpoints in this open-label study.
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- 05 Aug, 2020
Family Telehealth Project for Foster Care Youth
The purpose of this research is to adapt and evaluate the efficacy of an existing family based intervention to be delivered via telehealth to child welfare-involved (CWI) youth in out-of-home placement and their caregiver of origin.
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- 05 Aug, 2020
Prevention of Maternal Hypotension During Cesarean Section With Norepinephrine Infusion.
This will be a randomized study aiming at investigating the combination of a norepinephrine infusion and colloid preloading versus the combination of a norepinephrine infusion and crystalloid co-loading for the prevention of maternal hypotension during elective cesarean section
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- 16 Feb, 2024
- 2 locations
Personalized Extended Interval Dosing of Natalizumab in Relapsing Remitting Multiple Sclerosis
The influence of personalized dosing on pharmacokinetics will be monitored. Furthermore, personalized extended interval dosing will be studied in a subgroup with the aim to explore lower than previously studied trough values of natalizumab.
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- 16 Feb, 2024
- 15 locations
Implementation of an Early Rehabilitation Program for the Patient With Lung Transplantation: From the ICU to Home.
Methodology: A single-blind randomized clinical trial will be performed to divide patients with PT into one experimental group and another control group. Prior to the PT, those patients between the ages of 18 and 70 will be recruited, to be admitted to the ICU of Vall Hebron University Hospital, and …
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- 16 Feb, 2024
- 1 location
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy
Adult participants with locally advanced or MBC that is not amenable to curative therapy will be enrolled. Around 42 participants will be enrolled at approximately 20 sites worldwide. Venetoclax and capecitabine will be administered on a 21-day cycle.
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- 16 Feb, 2024
- 16 locations
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease
Participants will have a complete eye exam. They will read letters from a chart. Their eye pressure will be measured. Their pupils may be dilated with eye drops. Pictures of their eye will be taken. Lights will be shined in their eyes. Participants will take a visual field test.
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- 16 Feb, 2024
- 2 locations
Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the prevention of maternal hypotension in elective cesarean section
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- 16 Feb, 2024
- 1 location
tDCS in Post-stroke Neglect Rehabilitation
StarStim tDCS 8 channels Multisite device will be used.
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- 16 Feb, 2024
- 1 location