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Found 1816 clinical trials
A Study to Look at How Safe NNC0472-0147 is in Healthy People and in People With Type 2 Diabetes

Participants will get once daily injections of either NNC0472-0147 or insulin glargine for a treatment period of fourteen days. The injections will be given under the skin (subcutaneously, s.c.) of the left thigh. Participants will be in the study for about 7 weeks. There will be 15 visits with the …

low density lipoprotein
bilateral salpingectomy
bilateral oophorectomy
hysterectomy
type 2 diabetes mellitus
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Helping Families Pilot of a Family Resilience Program for Families Experiencing Homelessness and Parental Substance Use

Our primary hypothesis is that the adapted family resilience program will be feasible and acceptable to families with a recent history of homelessness and parental substance use disorder. Families that are eligible to participate in the study will be assigned randomly to one of two groups, 1) adapted family resilience …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Even if chronicity leads us to think about the stabilization of the physical condition, It is thought that the best results will be found among the subjects who will use the App.

hemiparesis
stroke
physical rehabilitation
hemiplegia
hemiplegia or hemiparesis
  • 0 views
  • 16 Feb, 2024
  • 1 location
TKR Rehabilitation Through the Immersive Virtual Reality in Aquatic Scenarios

Assessments will be performed at baseline and at the end of treatment.

cognitive disorders
edema
epilepsy
hydrotherapy
drainage
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

solid tumor
gonadotropin
cancer
human chorionic gonadotropin
hair thinning
  • 0 views
  • 16 Feb, 2024
  • 5 locations
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Phase 3 is a randomized open-label crossover study comparing the final oral ASTX030 tablet to SC azacitidine. The duration of the study is expected to be approximately 36 months.

dysplasia
anemia
myelodysplastic syndrome
myelodysplastic/myeloproliferative neoplasm
ringed sideroblasts
  • 0 views
  • 16 Feb, 2024
  • 2 locations
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

KEAP1/NRF2 mutation status (for eligibility) and STK11/LKB1 status (for stratification) will be determined by next generation sequencing. A commercial liquid biopsy (circulating tumor DNA) NGS test will be provided to study participants free of charge.

stage iv non-small cell lung cancer
STK11
pembrolizumab
vitamin b12 level
LKB1
  • 0 views
  • 16 Feb, 2024
  • 28 locations
CO2 Laser Revision for Burn Related Donor Site Scars

Patients will receive the standard fractional ablative CO2 treatments to their scars resulting from burn wounds allowed to heal by secondary intention and/or those treated with skin grafts. These will be prospectively observed for the duration of the study as well as adjacent normal skin. In addition, a donor site …

laser therapy
third degree burn
occupational therapies
compression therapy
scarring
  • 0 views
  • 05 Aug, 2020
NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

The purpose of this Phase I study is to determine the recommended phase 2 dose (RP2D) and safety profile of NBTXR3 activated by radiation therapy for the treatment of patients with pancreatic cancer that has spread to nearby tissues or lymph nodes (locally advanced) or may be able to be

pancreatic cancer
platelet count
cancer
capecitabine
resectable pancreatic cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Analgesic Effect of Oral Glucose in Neonates

However, it has been shown that neurological system known to be associated with pain transmission and modulation, is intact and functional. OBJECTIVE: Our objective is to determine if a 30% glucose solution would reduce pain after circumcision compared with normal saline.

nervousness
oximetry
circumcision
analgesics
  • 0 views
  • 16 Feb, 2024
  • 1 location