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Found 654 clinical trials
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years. But high-grade tumors can be very aggressive. Researchers want to learn more about this type of cancer. This may help them …

gastrin
chromogranin a
dotatate
vasoactive intestinal peptide
neuroendocrine tumor
  • 0 views
  • 05 Aug, 2020
ASHCOM Shoulder System and Its Related Instruments

The objectives of this study are to confirm safety, performance and clinical benefits of the ASHCOM Shoulder System and its related instruments by analysis of standard scoring systems, radiographs and adverse event records.

deficiency
total shoulder replacement
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 Patients  

This is a prospective, non-interventional, non-comparative, multicenter study to collect data on HT-1 patients in China treated with Nitisinone in a routine clinical setting. No tests or examinations are mandated in the study.

  • 0 views
  • 28 Feb, 2024
  • 2 locations
Asthma: Phenotyping Exacerbations 2

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

skin prick
prick skin
maintenance therapy
spirometry
corticosteroids
  • 0 views
  • 16 Feb, 2024
  • 1 location
Asthma: Phenotyping EXacerbations

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

skin prick
prick skin
maintenance therapy
spirometry
corticosteroids
  • 0 views
  • 16 Feb, 2024
  • 1 location
Post-Neoadjuvant Treatment MRI Based AI System to Predict pCR for Rectal Cancer

In this study, investigators seek for a better way to identify the potential pathologic complete response (pCR) patients form non-pCR patients with locally advanced rectal cancer (LARC), based on their post-neoadjuvant treatment Magnetic Resonance Imaging (MRI) data. Previously, a post neoadjuvant treatment MRI based radiomics AI model had been constructed …

adenocarcinoma
rectal cancer
MRI
adenocarcinoma of rectum
adjuvant therapy
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Standalone OMNI Surgical System for Open-angle Glaucoma

The emergence of minimally invasive glaucoma surgeries (MIGS) has seen a variety of potential innovative surgical alternatives to help better control intraocular pressure (IOP). The OMNI Surgical System (Sight Sciences, Menlo Park, CA, USA) is a promising MIGS procedure. It combines two procedures known as trabeculotomy and viscodilation of Schlemm's …

laser trabeculoplasty
ophthalmic surgery
trabeculotomy
glaucoma surgery
intraocular pressure
  • 0 views
  • 16 Feb, 2024
  • 1 location
Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU

This is a case series of patients with COVID-19 admitted to the largest university hospital in Sao Paulo, Brazil, during the 2020 COVID-19 pandemic. Data will be collected prospectively and retrospectively. The main objective is to describe the characteristics of critically ill patients with COVID-19 and their clinical outcomes, and …

critically ill
critical illness
covid-19
  • 0 views
  • 01 Feb, 2023
  • 1 location
Effect of COVID-19 Pandemic on Perceived Stress Anxiety Mood and Training Quality in Elite Athletes.

In this study, we aim to investigate stress, anxiety, mood, life satisfaction measures among elite athletes during COVID-19 and explore the relationship between these measures and the changes in training characteristics in elite athletes during the COVID-19 pandemic.

anxiety
covid-19
  • 0 views
  • 05 Aug, 2020
Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer

In this study, investigators utilize a radiomics prediction model to predict the tumor response to neoadjuvant chemoradiotherapy (nCRT) before the nCRT is administered for patients with locally advanced rectal cancer (LARC). Previously, the radiomics prediction model has been constructed based on the radiomics features extracted from pretreatment Magnetic Resonance Imaging …

adjuvant
adenocarcinoma
adjuvant chemotherapy
rectal cancer
MRI
  • 0 views
  • 16 Feb, 2024
  • 3 locations