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Found 1429 clinical trials
The Effect of a Low FODMAP Diet in Irritable Bowel Syndrome Patients

Tertiary care IBS patients will be recruited for a prospective low FODMAP intervention study, hereby focusing on the reintroduction phase of the diet, where patients are blindly challenged with different FODMAP groups administered as powder, to be added to the strict FODMAP exclusion phase. During the screening phase of two …

fodmap diet
irritable bowel syndrome
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation. Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

oximetry
single lung ventilation
postoperative pain
analgesia
one lung ventilation
  • 0 views
  • 16 Feb, 2024
  • 1 location
18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer

The scan will be used to see how the disease has spread. Both the treatment strategies and probable disease outcomes as relevant to clinical endpoints will be assessed. This study is open to Veterans only.

metastatic prostate cancer
ct scan
pet/ct scan
adenocarcinoma
external beam radiation therapy
  • 0 views
  • 05 Aug, 2020
Helping Families Pilot of a Family Resilience Program for Families Experiencing Homelessness and Parental Substance Use

For the families assigned to the treatment as usual group, they will continue to receive case management services from their residential facilities. Families in both groups will be asked to fill out 3 surveys (one at the beginning of the program, one at the end of the program, and at …

  • 0 views
  • 16 Feb, 2024
  • 1 location
The Young Heart Study

The purpose of our project is to better understand the characteristics of the young patients with coronary artery disease presenting for cardiac catheterization at our institution and to put forth a program to optimize their risk factors with a focus on gender differences. We will assess traditional and non-traditional risk …

cardiovascular disease
depression
anxiety
arterial disease
heart study
  • 0 views
  • 16 Feb, 2024
  • 1 location
Feasibility and Effectiveness of Delivering Cognitive Behaviour Therapy Through Online Psychotherapy Tool (OPTT) for Depression

This study also aims to determine the difference in efficacy between e-CBT alone, pharmacotherapy alone and e-CBT with pharmacotherapy as it relates to various demographic characteristics (i.e., gender, age, socioeconomic status, etc.). To the principal investigators' knowledge, this study will be the first multi-site study examining the efficacy of e-CBT …

psychiatric disorder
major depressive disorder
depression
anxiety
depressive disorder
  • 0 views
  • 16 Feb, 2024
  • 1 location
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them …

measurable disease
gilbert's syndrome
lymphoma
revlimid
oral contraceptives
  • 0 views
  • 16 Feb, 2024
  • 1 location
Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

The primary hypothesis is that pembrolizumab + lenvatinib is superior to SOC chemotherapy with respect to ORR per modified Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by blinded independent central review.

measurable disease
carboplatin
carcinoma
antihypertensive
paclitaxel
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

In light of the emerging literature demonstrating that Transcranial Magnetic Stimulation (TMS) improves general cognition in subjects with Alzheimer Disease (AD), the investigators propose to study the effectiveness of TMS as a therapy for impaired verbal communication. The hypothesis to be tested is that TMS combined with Constraint Induced Language …

cognitive impairment
alzheimer's disease
mini-mental state examination
  • 0 views
  • 16 Feb, 2024
  • 1 location
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

Lenvatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

bilirubin levels
lenvatinib
cancer
monoclonal antibodies
beta human chorionic gonadotropin
  • 8 views
  • 05 Aug, 2020
  • 1 location