Found 609 clinical trials
Trial for prescreener data migration( dont use it)
Trial for prescreener data migration( dont use it)
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- 15 Jul, 2024
- 1 location
A Rhinovirus Challenge Study to Investigate Exacerbations and Immune Responses in Bronchiectasis (BARRIER)
The goal of this study is to determine if viral infection with the common cold leads to an exacerbation in participants with bronchiectasis. We will compare the participants with bronchiectasis to a group of healthy participants. The main questions it aims to answer are:Does viral infection with the common cold …
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- 23 Apr, 2025
- 1 location
Description of Patients With Type 1 Diabetes Treated With Teplizumab (TEPLI-REAL)
Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease caused by the destruction of pancreatic β cells. T1D pathogenesis progresses through several stages: Stage 1 T1D includes the presence of β cell autoimmunity and thus presence of islet autoantibodies, without the presence of dysglycemia and symptoms. Stage 2 T1D …
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- 25 Apr, 2025
Progress Complication
Coronary angiography and percutaneous coronary intervention (PCI) is often performed in patients with ischemic heart disease. The safety of PCI has improved with new devices and strategies, but complications still occur, especially during complex procedures. The objectives of this multi-center observational registry are to examine frequency of complications occuring during …
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- 14 Mar, 2022
- 1 location
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study) (EXE-T1D)
Type 1 diabetes (T1D) results from destruction of insulin-producing beta cells in the pancreas by the body's own immune system (autoimmunity). It is not fully understood what causes this type of diabetes and why there is variation in age of onset and severity between people who develop the disease. The …
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- 04 Jul, 2023
- 3 locations
Hypertension Management in Family Practice
High blood pressure is the greatest threat to the global burden of disease, contributing to an estimated 9.4 million deaths a year. Cardiovascular disease morbidity and mortality are positively correlated with the degree of elevation of blood pressure, without any evidence of a threshold down to at least 115/75 mm …
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- 08 Nov, 2022
- 3 locations
Prospective Validation and Application of an Artificial Intelligence-based Model for Evaluating the Efficacy of Breast Cancer Patients After Neoadjuvant Therapy
Breast cancer has become the world's number one cancer. While its therapeutic efficacy is increasing, how to achieve non-invasive evaluation of the efficacy of neoadjuvant therapy (NAT) for breast cancer patients and thus avoid surgery has become a bottleneck problem that needs to be broken through in clinical diagnosis and …
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- 18 Jul, 2025
- 1 location
Tissue Models for Liver Disease (TIMOLD)
The human immune response to bacterial and viral local and systemic infection are fairly well understood, but we lack details on the earliest phases. Better knowledge of these events would be important for the prevention and treatment of severe bacterial or viral disease. From models of infection, we have data …
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- 24 May, 2022
- 1 location
Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital (COPACNE)
With 24 million results associated with Google's searchon keywords "severe acne", Pr Dreno's team understand better thatthis disease, which affects many French people, is a real concern of Public Health and not a "forced evil" of the adolescent period, which will eventually resolve itself. Acne does not affect the vital …
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- 31 May, 2024
- 1 location