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Found 141 clinical trials
Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

This study compares gadolinium contrast-enhanced Abbreviated MRI (AMRI) to standard ultrasound for Hepatocellular Carcinoma (HCC) screening and surveillance in subjects with liver cirrhosis.

hepatocellular carcinoma
carcinoma
cirrhosis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

The purpose of this project is to realize a randomized open-label study (EudraCT number: 2020-000120-19) to evaluate the safety and the anti-tumor activity of peptide(s)-based immunotherapy in an umbrella window pre-operative opportunity phase II study in patients with squamous cell carcinoma of the head and neck.

metastasis
carcinoma in situ of the cervix
measurable disease
cavity
io102
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Standard Nutrition Therapy on Nutritional Status and Prognosis in Locoregionally Advanced Nasopharyngeal Carcinoma Patients With Malnutrition

The purpose of this study is to evaluate the efficacy of standard nutrition treatment versus conventional nutrition treatment in local advanced nasopharyngeal carcinoma patients.

malnutrition
nasopharyngeal carcinoma
cisplatin
renal function test
digestive system disease
  • 0 views
  • 05 Aug, 2020
Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma

If the hypothesis is confirmed, it is expected to provide a convenient choice for the surgical treatment of localized recurrent nasopharyngeal carcinoma.

radiofrequency ablation
cancer
  • 0 views
  • 05 Aug, 2020
A Study of Anti-PD-1/CTLA-4 Bispecific AK104 Plus Lenvatinib in First-line Advanced Hepatocellular Carcinoma

An open-label multi-center phase Ib/II study to evaluate the efficacy and safety of anti-PD-1/CTLA-4 bispecific antibody AK104 plus lenvatinib as the first-line therapy for patients with advanced hepatocellular carcinoma.

lenvatinib
hepatocellular carcinoma
measurable disease
carcinoma
  • 0 views
  • 05 Aug, 2020
Combined Locoregional Treatment With Immunotherapy for Unresectable HCC.

Efficacy and Safety of Locoregional treatments Combined With PD-1 Inhibitor in Patients With Unresectable Hepatocellular Carcinoma.

unresectable hepatocellular carcinoma
pd-1 inhibitor
hepatocellular carcinoma
TACE
carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Role of CEUS as a Secondary Diagnostic Modality

To determine the role of contrast-enhanced ultrasound (CEUS) as a second-line imaging modality after gadoxetate-enhanced MRI (Gd-EOB-MRI) for identifying hepatocellular carcinoma (HCC) among at-risks observations.

hepatocellular carcinoma
contrast-enhanced ultrasound
carcinoma
  • 0 views
  • 05 Aug, 2020
Pembrolizumab Plus Paclitaxel Cisplatin Followed by Surgery for Locally Advanced ESCC

The purpose of this study is to observe and evaluate the efficacy and safety of pembrolizumab plus paclitaxel, cisplatin followed by Da Vinci robot radical surgery for locally advanced esophageal squamous cell carcinoma.

pembrolizumab
squamous cell carcinoma of esophagus
cisplatin
urine test
paclitaxel
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of AK104 a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer

This is a Phase 2, global, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic cervical carcinoma.

metastasis
cervical cancer
squamous cell carcinoma
carcinoma
metastatic cervical carcinoma
  • 0 views
  • 16 Feb, 2024
  • 20 locations
Radical Radiotherapy and Chemotherapy Combined With Maintenance Chemotherapy in the Treatment of Stage N3 NPC

This study is a randomized, phase II, prospective, multicenter clinical trial to evaluate the efficacy and safety of radical chemoradiotherapy plus oral capecitabine/teggio for 1 year in patients with N3.

nasopharyngeal biopsy
capecitabine
nasopharyngeal carcinoma
carcinoma
chemoradiotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location