Found 401 clinical trials
A RCT - Safety & Efficacy of Tocilizumab - Tx of Severe COVID-19: ARCHITECTS
The overall objective is to evaluate the clinical efficacy and safety of tocilizumab relative to placebo among approximately 300 hospitalized adult patients who have severe COVID-19. The study will be a 2 arm double blinded comparison between tocilizumab 8 mg/kg and matching placebo IV. The dose may be repeated in …
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- 16 Feb, 2024
- 1 location
Efficacy Assessment of Methylprednisolone and Heparin in Patients With COVID-19 Pneumonia
The COVID-19 pandemic has been spreading continuously, and in Brazil, until July 19, 2020, there have been more than 2,000,000 cases with more than 79,000 deaths, with daily increases.
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- 05 Aug, 2020
Trial of Inhaled Anti-viral (SNG001) for SARS-CoV-2 (COVID-19) Infection
If SNG001 proves to be beneficial it would be a major breakthrough for the treatment of COVID-19.
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- 01 Feb, 2023
- 9 locations
Study of LAU-7b for the Treatment of COVID-19 Disease in Adults
A randomized, double-blind, placebo-controlled Phase 2 Study of LAU-7b against confirmed COVID-19 Disease in hospitalized patients at a higher risk of complications.
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- 05 Aug, 2020
The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients
This study is a multi-center, randomized, double-blind, parallel, placebo-controlled, phase clinical trial to evaluate efficacy and safety of Pyramax in mild to moderate COVID-19 patients.
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- 05 Aug, 2020
Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19
Low radiation doses produce anti-inflammatory effects, which may be useful in the treatment of respiratory complications of COVID-19. This type of treatment is non-invasive and therefore, a priori, it can be used in all types of patients. Main objective: To evaluate the efficacy of low-dose lung irradiation as an adjunctive …
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- 16 Feb, 2024
- 3 locations
Efficacy and Safety of Polyoxidonium in Hospitalized Patients With Coronavirus Disease COVID-19
The purpose of this study is to demonstrate the superiority of Polyoxidonium, lyophilizate for solution for injections and topical application, 6 mg over placebo in hospitalized patients with coronavirus disease (COVID-19). This is a multicentre prospective, randomized, double-blind, placebo-controlled, parallel-group phase IIb\IIIa clinical trial.
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- 16 Feb, 2024
- 12 locations
Study of Ampion for the Treatment of Adult COVID-19 Patients Requiring Oxygen Supplementation
This is a Phase 1 randomized study to evaluate the safety, tolerability and efficacy of IV Ampion in improving the clinical course and outcomes of patients hospitalized with COVID-19 infection who require supplemental oxygen.
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- 05 Aug, 2020
Evaluation of Staff COVID-19 Wellbeing Centres in a Healthcare Workplace: COVID-WELL Study
Evaluation of a workplace intervention to implement supported wellbeing centres in a healthcare workplace during and after the COVID-19 pandemic. Mixed-Methods Evaluation study - including collection of service use monitoring data, online survey and qualitative interviews.
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- 16 Feb, 2024
- 1 location
Psychological Intervention for Parent-child Relationship and Couple Relationship Under COVID-19 in China
Under the COVID-19, individuals who were home Quarantine experienced new challenges on their parent-child relationship and couple relationship. The current project aimed to provide psychological interventions for both parents and couples in order to improving their relationship.
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- 16 Feb, 2024
- 1 location