Found 127 clinical trials
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms
The study is a prospective, randomized, controlled investigation designed for comparison of two groups for the reduction of respiratory distress in a CoViD-19 population, using gammaCore Sapphire (nVNS) plus standard of care (active) vs. standard of care alone (SoC), the control group. The gammaCore (nVNS) treatments will be used acutely …
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- 16 Feb, 2024
- 1 location
Swiss Pediatric Heart Cohort
The Swiss Pediatric Heart Cohort aims to collect representative longitudinal data on all children diagnosed with a clinically relevant heart disease in Switzerland. The long-term goal is to optimize diagnosis and therapy, and to allow setting up national research projects.
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- 16 Feb, 2024
- 1 location
DeBakey Cardiovascular Magnetic Resonance Study
CMR techniques to be studies include function, fibrosis, and flow. Focus areas include valvular heart disease, ischemic heart disease, cardiomyopathies, and vascular disease.
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- 16 Feb, 2024
- 1 location
Progress Complication
Coronary angiography and percutaneous coronary intervention (PCI) is often performed in patients with ischemic heart disease. The safety of PCI has improved with new devices and strategies, but complications still occur, especially during complex procedures.
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- 14 Mar, 2022
- 1 location
Study on Optimal Treatment Strategy for Elderly Patients With High-risk Complex Aortic Valve Disease
Aortic valve disease (AVD) is the most common and age-related mortality in elderly patients with valvular heart disease (VHD). Although transcatheter aortic valve replacement (TAVR) has been recommended at a higher level in foreign guidelines, there are still many high-risk and severe elderly patients with VHD who have not received …
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- 15 Sep, 2021
- 1 location
Prediction of Outcome by Echocardiography in Left Bundle Branch Block
Patients with left bundle branch block have an increased risk for the development of heart-failure and death. However, risk factors for unfavorable outcomes are still poorly defined. This study aims to identify echocardiographic parameters and ECG characteristics by machine learning in order to develop individual risk assessment
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- 16 Feb, 2024
- 1 location
A Blind Self Controlled Multicenter Clinical Trial on the Effectiveness and Safety of Noninvasive Flow Reserve Score Analysis Software for Coronary Angiography
This is a blind evaluation, self-control, multicenter clinical trial. 340 patients who need selective operation to evaluate the function of coronary artery were selected and measured with ctffr and FFR. The data of the experimental group was defined as: FFR value at the distal end of stenosis was obtained by …
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- 16 Feb, 2024
- 1 location
Pathogenesis and Mechanisms of Mitral Annular Calcification
Researchers are testing blood or mitral valve tissue to better understand the reasons why Mitral Annular Calcification (MAC) develops in patients with heart disease.
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- 16 Feb, 2024
- 1 location
Comparison of Cardiac Function Between Left Bundle Branch Pacing and Right Ventricular Outflow Tract Septal Pacing in Pacemaker-dependent Patients
The safety and feasibility of permanent HIS bundle pacing have been confirmed in patients with various cardiac diseases. However, the shortcomings of high and unstable threshold, long implantation time, low R-wave amplitude and HIS bundle damage during implantation limit the application of HIS pacing especially in patients with infra-Hisian block.
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- 16 Feb, 2024
- 1 location
Immune Biomarkers of Outcome From COVID-19
Information we have so far about COVID-19 suggests that people with underlying conditions, such as high blood pressure and heart disease, or older people are at higher risk of having severe illness. Scientists do not yet understand why but think it may be related to the immune system.
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- 16 Feb, 2024
- 1 location