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Found 66 clinical trials
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

luteinizing hormone
serum testosterone
darolutamide
antiandrogen therapy
gonadotropin releasing hormone
  • 0 views
  • 05 Aug, 2020
Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer

This is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual of 50 patients.

stereotactic body radiation therapy
adenocarcinoma of prostate
hbed-cc
metastasis
adenocarcinoma
  • 16 views
  • 05 Aug, 2020
Cost Talk: Discussing Cancer Care Costs

The purpose of this study is to investigate whether an encounter decision aid (used during a consultation) containing cost information about options, combined with clinician training about cost discussions and available financial resources, influence surgeon-patient cost conversations, referrals to address costs, patients' financial stress, and high-quality decision-making for patients with …

cancer care
prostate specific antigen
  • 0 views
  • 16 Feb, 2024
  • 1 location
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

5-fraction SABR is a feasible, well-tolerated, effective and cost effective treatment for high-intermediate and high risk prostate cancer with/without an image-guided intraprostatic boost.

stereotactic body radiation therapy
adenocarcinoma
adenocarcinoma of prostate
  • 0 views
  • 16 Feb, 2024
  • 1 location
Impact of Acetazolamide in Reducing Referred Postoperative Pain

Robotic assisted laparoscopic prostatectomy (RALP) is the standard treatment for prostate cancer, due to the benefits of decreased blood loss and length of stay.The procedure involves removing a man's prostate using a minimally invasive robotic approach under the guidance of a surgeon.

laparoscopy
cancer
prostatectomy
analgesia
prostate cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Tasquinimod for the Treatment of Relapsed or Refractory Myeloma

This study is the first study of tasquinimod, an inhibitor of S100A9, in patients with multiple myeloma.

multiple myeloma
measurable disease
  • 0 views
  • 05 Aug, 2020
Lutetium-177-PSMA Radioligand Therapy in Advanced Salivary Gland Cancer Patients

Phase 2 pilot study, which evaluates the safety and efficacy of Lutetium-177-PSMA radioligand therapy in advanced salivary gland cancer patients.

metastasis
cancer
adenoid cystic carcinoma
neutrophil count
salivary gland cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Prostate Screening for Men With Inherited Risk of Developing Aggressive Prostate Cancer PATROL Study

This study investigates ways to detect prostate cancer earlier in men who are at increased genetic risk of developing prostate cancer that forms, grows, or spreads quickly (aggressive).

cancer therapy
PMS2
adenocarcinoma of prostate
BRCA2
carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer MIRAGE Study

This phase III trial studies compares CT-guided stereotactic body radiation therapy and MRI-guided stereotactic body radiation therapy (SBRT) in treating prostate cancer. Image-guided SBRT is a standard treatment for prostate cancer, which combines imaging of the cancer within the body with the delivery of therapeutic radiation doses produced on a …

seminal vesicles
stereotactic body radiation therapy
bone scan
metastasis
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Immune Profiling After HDR in Local Relapsed Prostate Cancer

The main-hypothesis is that HDR-brachytherapy will turn an immunologically "cold" (no T-cell infiltrations) prostate cancer into an immunologically "hot" (CD4 and CD8-cell infiltrations) tumor, creating leverage points for different forms of IO.

brachytherapy
primary tumor
tumor cells
multiparametric magnetic resonance imaging
  • 0 views
  • 16 Feb, 2024
  • 1 location